A One Health approach to the epidemiology, management, surveillance, and control of
leptospirosis relies on accessible and accurate diagnostics that can be applied to humans …

CRISPR/Cas technology originated from the immune mechanism of archaea and bacteria
and was awarded the Nobel Prize in Chemistry in 2020 for its success in gene editing …

Extensive testing is essential to break the transmission of SARS-CoV-2, which causes the
ongoing COVID-19 pandemic. Here, we present a CRISPR-based diagnostic assay that is …

Abstract Background The CRISPR-Cas13 system is an RNA-guided RNA-targeting system
and has been widely used in transcriptome engineering with potentially important clinical …

Rapid, point-of-care (POC) diagnostics are essential to mitigate the impacts of current (and
future) epidemics; however, current methods for detecting severe acute respiratory …

For some Cas nucleases, trans-cleavage activity triggered by CRISPR/Cas-mediated cis-
cleavage upon target nucleic acid recognition has been explored for diagnostic detection …

The CRISPR-Cas13 system is an RNA-guided RNA-targeting system, and has been widely
used in transcriptome engineering with potentially important clinical applications. However …

Over the past decades, there have been numerous outbreaks, including parasitic, fungal,
bacterial, and viral infections, worldwide. The rate at which infectious diseases are emerging …

The coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), remains a global threat with an ever-increasing death toll …

Objective To estimate the accuracy of clustered regularly interspaced short palindromic
repeats (CRISPR) in determining coronavirus disease-19 (COVID-19). Methods As of …