Integrins are heterodimeric cell surface receptors ensuring the mechanical connection
between cells and the extracellular matrix. In addition to the anchorage of cells to the …

Virus–receptor interactions play a key regulatory role in viral host range, tissue tropism, and
viral pathogenesis. Viruses utilize elegant strategies to attach to one or multiple receptors …

More than 80 different adenovirus (AdV) types infect humans through the respiratory, ocular,
or gastrointestinal tracts. They cause acute clinical mani-festations or persist under humoral …

Viral capsids are often regarded as inert structural units, but in actuality they display
fascinating dynamics during different stages of their life cycle. With the advent of single …

Abstract Human Adenoviruses (HAdVs) are a family of clinically and therapeutically relevant
viruses. A precise understanding of their host cell attachment and entry mechanisms can be …

Adenovirus (AdV) capsid organization is considerably complex, not only because of its large
size (~ 950 Å) and triangulation number (pseudo T= 25), but also because it contains four …

Viruses are spherical or complex shaped carriers of proteins, nucleic acids and sometimes
lipids and sugars. They are metastable and poised for structural changes. These features …

Viral particle binding to plasma membrane receptors elicits virus motions, recruits signaling
proteins, and triggers membrane bending and fission, finally resulting in endocytic virus …

Although coagulation factors play a role in host defense for “living fossils” such as
horseshoe crabs, the role of the coagulation system in immunity in higher organisms …

Here we review the current knowledge on maturation of adenovirus, a non-enveloped
icosahedral eukaryotic virus. The adenovirus dsDNA genome fills the capsid in complex with …