Extrapulmonary tuberculosis

SK Sharma, A Mohan - Indian Journal of Medical Research, 2004 - search.proquest.com
Extrapulmonary involvement can occur in isolation or along with a pulmonary focus as in the
case of patients with disseminated tuberculosis (TB). The recent human immunodeficiency …

Tuberculous meningitis: many questions, too few answers

GE Thwaites, TT Hien - The Lancet Neurology, 2005 - thelancet.com
Tuberculous meningitis (TM) is difficult to diagnose and treat; clinical features are non-
specific, conventional bacteriology is widely regarded as insensitive, and assessment of …

Guidelines for the acute treatment of cerebral edema in neurocritical care patients

AM Cook, G Morgan Jones, GWJ Hawryluk, P Mailloux… - Neurocritical care, 2020 - Springer
Background Acute treatment of cerebral edema and elevated intracranial pressure is a
common issue in patients with neurological injury. Practical recommendations regarding …

Tuberculous meningitis: a uniform case definition for use in clinical research

S Marais, G Thwaites, JF Schoeman… - The Lancet infectious …, 2010 - thelancet.com
Tuberculous meningitis causes substantial mortality and morbidity in children and adults.
More research is urgently needed to better understand the pathogenesis of disease and to …

Dexamethasone for the treatment of tuberculous meningitis in adolescents and adults

GE Thwaites, ND Bang, NH Dung… - … England Journal of …, 2004 - Mass Medical Soc
Background Tuberculous meningitis kills or disables more than half of those affected with
the disease. Previous studies have been too small to determine whether adjunctive …

British Infection Society guidelines for the diagnosis and treatment of tuberculosis of the central nervous system in adults and children

G Thwaites, M Fisher, C Hemingway, G Scott… - Journal of infection, 2009 - Elsevier
The aim of these guidelines is to describe a practical but evidence-based approach to the
diagnosis and treatment of central nervous system tuberculosis in children and adults. We …

Evaluation of GeneXpert MTB/RIF for diagnosis of tuberculous meningitis

NTQ Nhu, D Heemskerk, DDA Thu… - Journal of clinical …, 2014 - journals.asm.org
Tuberculous meningitis (TBM) is the most severe form of tuberculosis. Microbiological
confirmation is rare, and treatment is often delayed, increasing mortality and morbidity. The …

Tuberculous meningitis

G Thwaites, TTH Chau, NTH Mai… - Journal of Neurology …, 2000 - jnnp.bmj.com
Uncertainty and doubt dominate all aspects of tuberculous meningitis (TBM). The variable
natural history and accompanying clinical features of TBM hinders the diagnosis. Ziehl …

A polymorphism in human TLR2 is associated with increased susceptibility to tuberculous meningitis

NTT Thuong, TR Hawn, GE Thwaites, TTH Chau… - Genes & …, 2007 - nature.com
Tuberculous meningitis (TBM) results from the haematogenous dissemination of
Mycobacterium tuberculosis from the lung to the brain. Dissemination is believed to occur …

Tuberculous meningitis in adults: a review of a decade of developments focusing on prognostic factors for outcome

F Brancusi, J Farrar, D Heemskerk - Future microbiology, 2012 - Taylor & Francis
Tuberculous meningitis (TBM) is the most severe form of TB. Despite treatment, mortality and
long-term disability remain unacceptably high. Prevention, early recognition, diagnosis and …