Status of polymer fused deposition modeling (FDM)-based three-dimensional printing (3DP) in the pharmaceutical industry

H Iqbal, Q Fernandes, S Idoudi, R Basineni, N Billa - Polymers, 2024 - mdpi.com
Additive manufacturing (AM) or 3D printing (3DP) is arguably a versatile and more efficient
way for the production of solid dosage forms such as tablets. Of the various 3DP …

Fabrication of timed-release indomethacin core–shell tablets for chronotherapeutic drug delivery using dual nozzle fused deposition modeling (FDM) 3D printing

S Chung, P Zhang, MA Repka - European Journal of Pharmaceutics and …, 2023 - Elsevier
In the present study, timed-release indomethacin tablets, releasing drug after predetermined
lag times, were developed for the effective treatment of early morning stiffness in rheumatoid …

[HTML][HTML] 3D printed mucoadhesive orodispersible films manufactured by direct powder extrusion for personalized clobetasol propionate based paediatric therapies

GF Racaniello, M Pistone, C Meazzini… - International Journal of …, 2023 - Elsevier
The aim of this work is the development and production by Direct Powder Extrusion (DPE)
3D printing technique of novel oral mucoadhesive films delivering Clobetasol propionate …

Fabrication of suppository shells via hot-melt extrusion paired with fused deposition modeling 3D printing techniques

P Zhang, H Wang, S Chung, J Li, SK Vemula… - Journal of Drug Delivery …, 2024 - Elsevier
Abstract Three-dimensional (3D) printing is a potential technique for develo**
personalized medicines. Among its applications, mold manufacturing in industrial 3D …

[HTML][HTML] Enhancing Patient-Centric Drug Development: Coupling Hot Melt Extrusion with Fused Deposition Modeling and Pressure-Assisted Microsyringe Additive …

D Nyavanandi, P Mandati, N Vidiyala, P Parupathi… - Pharmaceutics, 2024 - mdpi.com
In recent years, with the increasing patient population, the need for complex and patient-
centric medications has increased enormously. Traditional manufacturing techniques such …

Development of multiple structured extended release tablets via hot melt extrusion and dual-nozzle fused deposition modeling 3D printing

P Zhang, J Li, EA Ashour, S Chung, H Wang… - International Journal of …, 2024 - Elsevier
The study aims to fabricate extended release (ER) tablets using a dual-nozzle fused
deposition modeling (FDM) three-dimensional (3D) printing technology based on hot melt …

Hard gelatin capsules containing hot melt extruded solid crystal suspension of carbamazepine for improving dissolution: Preparation and in vitro evaluation

S Narala, N Komanduri, D Nyavanandi… - Journal of drug delivery …, 2023 - Elsevier
Aqueous solubility is one of the key parameters for achieving the desired drug concentration
in systemic circulation for better therapeutic outcomes. Carbamazepine (CBZ) is practically …

API and polymer selection: formulation and process variables

SK Vemula, AP Padakanti, N Chella, S Narala… - 3D printing: emerging …, 2023 - Springer
Successful 3D printability depends on various critical parameters. During formulation,
ensuring the stability of the active pharmaceutical ingredient (API) while processing and …

Electrospun Ibuprofen-Loaded Blend PCL/PEO Fibers for Topical Drug Delivery Applications

DB Mustafa, T Sakai, O Sato, M Ikebe, SF Chou - Polymers, 2024 - pmc.ncbi.nlm.nih.gov
Electrospun drug-eluting fibers have demonstrated potentials in topical drug delivery
applications, where drug releases can be modulated by polymer fiber compositions. In this …