Derivation and analysis of coupled PDEs on manifolds with high dimensionality gap arising from topological model reduction

F Laurino, P Zunino - ESAIM: Mathematical Modelling and …, 2019 - esaim-m2an.org
Multiscale methods based on coupled partial differential equations defined on bulk and
embedded manifolds are still poorly explored from the theoretical standpoint, although they …

A new simulation framework for soil–root interaction, evaporation, root growth, and solute transport

T Koch, K Heck, N Schröder, H Class… - Vadose zone …, 2018 - Wiley Online Library
Core Ideas We present a locally mass‐conservative flow, transport, and root–soil interaction
model. We include a sustainable, flexible research software framework for plant‐scale …

Mathematical modeling, analysis and numerical approximation of second-order elliptic problems with inclusions

T Köppl, E Vidotto, B Wohlmuth… - Mathematical Models and …, 2018 - World Scientific
Many biological and geological systems can be modeled as porous media with small
inclusions. Vascularized tissue, roots embedded in soil or fractured rocks are examples of …

Analysis and approximation of mixed-dimensional PDEs on 3D-1D domains coupled with Lagrange multipliers

M Kuchta, F Laurino, KA Mardal, P Zunino - SIAM Journal on Numerical …, 2021 - SIAM
Coupled partial differential equations (PDEs) defined on domains with different
dimensionality are usually called mixed-dimensional PDEs. We address mixed-dimensional …

A new framework for assessing subject-specific whole brain circulation and perfusion using MRI-based measurements and a multi-scale continuous flow model

E Hodneland, E Hanson, O Sævareid… - PLoS computational …, 2019 - journals.plos.org
A large variety of severe medical conditions involve alterations in microvascular circulation.
Hence, measurements or simulation of circulation and perfusion has considerable clinical …

A computational model for microcirculation including Fahraeus‐Lindqvist effect, plasma skimming and fluid exchange with the tissue interstitium

L Possenti, S Di Gregorio, FM Gerosa… - International Journal …, 2019 - Wiley Online Library
We present a two‐phase model for microcirculation that describes the interaction of plasma
with red blood cells. The model takes into account of typical effects characterizing the …

Splitting method for elliptic equations with line sources

IG Gjerde, K Kumar, JM Nordbotten… - … and Numerical Analysis, 2019 - esaim-m2an.org
In this paper, we study the mathematical structure and numerical approximation of elliptic
problems posed in a (3D) domain Ω when the right-hand side is a (1D) line source Λ. The …

Mathematical analysis, finite element approximation and numerical solvers for the interaction of 3d reservoirs with 1d wells

D Cerroni, F Laurino, P Zunino - GEM-International Journal on …, 2019 - Springer
We develop a mathematical model for the interaction of a three-dimensional reservoir with
the flow through wells, namely narrow cylindrical channels cutting across the reservoir. Leak …

Solving elliptic problems with singular sources using singularity splitting deep Ritz method

T Hu, B **, Z Zhou - SIAM Journal on Scientific Computing, 2023 - SIAM
In this work, we develop an efficient solver based on neural networks for second-order
elliptic equations with variable coefficients and a singular source. This class of problems …

A mixed finite element method to solve the EEG forward problem

J Vorwerk, C Engwer, S Pursiainen… - IEEE transactions on …, 2016 - ieeexplore.ieee.org
Finite element methods have been shown to achieve high accuracies in numerically solving
the EEG forward problem and they enable the realistic modeling of complex geometries and …