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γ-Aminobutyric acid (GABA) signalling in plants
The role of γ-aminobutyric acid (GABA) as a signal in animals has been documented for
over 60 years. In contrast, evidence that GABA is a signal in plants has only emerged in the …
over 60 years. In contrast, evidence that GABA is a signal in plants has only emerged in the …
The regulation of glutamic acid decarboxylases in GABA neurotransmission in the brain
SE Lee, Y Lee, GH Lee - Archives of pharmacal research, 2019 - Springer
Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter that is required for
the control of synaptic excitation/inhibition and neural oscillation. GABA is synthesized by …
the control of synaptic excitation/inhibition and neural oscillation. GABA is synthesized by …
ScanNet: an interpretable geometric deep learning model for structure-based protein binding site prediction
Predicting the functional sites of a protein from its structure, such as the binding sites of small
molecules, other proteins or antibodies, sheds light on its function in vivo. Currently, two …
molecules, other proteins or antibodies, sheds light on its function in vivo. Currently, two …
Discovery and characterization of gut microbiota decarboxylases that can produce the neurotransmitter tryptamine
Several recent studies describe the influence of the gut microbiota on host brain and
behavior. However, the mechanisms responsible for microbiota-nervous system interactions …
behavior. However, the mechanisms responsible for microbiota-nervous system interactions …
[HTML][HTML] Stiff-person syndrome and GAD antibody-spectrum disorders: GABAergic neuronal excitability, immunopathogenesis and update on antibody therapies
MC Dalakas - Neurotherapeutics, 2022 - Elsevier
Abstract Although antibodies against Glutamic Acid Decarboxylase (GAD) were originally
associated with Stiff Person Syndrome (SPS), they now denote the “GAD antibody-spectrum …
associated with Stiff Person Syndrome (SPS), they now denote the “GAD antibody-spectrum …
Maternal immune activation leads to selective functional deficits in offspring parvalbumin interneurons
Abnormalities in prefrontal gamma aminobutyric acid (GABA) ergic transmission, particularly
in fast-spiking interneurons that express parvalbumin (PV), are hypothesized to contribute to …
in fast-spiking interneurons that express parvalbumin (PV), are hypothesized to contribute to …
[HTML][HTML] GABAergic signaling as a potential therapeutic target in cancers
Y Yang, L Ren, W Li, Y Zhang, S Zhang, B Ge… - Biomedicine & …, 2023 - Elsevier
GABA is the most common inhibitory neurotransmitter in the vertebrate central nervous
system. Synthesized by glutamic acid decarboxylase, GABA could specifically bind with two …
system. Synthesized by glutamic acid decarboxylase, GABA could specifically bind with two …
GAD antibody-spectrum disorders: progress in clinical phenotypes, immunopathogenesis and therapeutic interventions
P Tsiortou, H Alexopoulos… - Therapeutic advances in …, 2021 - journals.sagepub.com
Antibodies against glutamic acid decarboxylase (GAD), originally linked to stiff person
syndrome (SPS), now denote the “GAD antibody-spectrum disorders”(GAD-SD) that also …
syndrome (SPS), now denote the “GAD antibody-spectrum disorders”(GAD-SD) that also …
[HTML][HTML] Biosynthesis of Gamma-Aminobutyric Acid (GABA) by Lactiplantibacillus plantarum in Fermented Food Production
In recent decades, given the important role of gamma-aminobutyric acid (GABA) in human
health, scientists have paid great attention to the enrichment of this chemical compound in …
health, scientists have paid great attention to the enrichment of this chemical compound in …
Interneuron accumulation of phosphorylated tau impairs adult hippocampal neurogenesis by suppressing GABAergic transmission
J Zheng, HL Li, N Tian, F Liu, L Wang, Y Yin, L Yue… - Cell stem cell, 2020 - cell.com
Phospho-tau accumulation and adult hippocampal neurogenesis (AHN) impairment both
contribute importantly to the cognitive decline in Alzheimer's disease (AD), but whether and …
contribute importantly to the cognitive decline in Alzheimer's disease (AD), but whether and …