Molecular recognition in chemical and biological systems

E Persch, O Dumele, F Diederich - … Chemie International Edition, 2015 - Wiley Online Library
Abstract Structure‐based ligand design in medicinal chemistry and crop protection relies on
the identification and quantification of weak noncovalent interactions and understanding the …

Mass spectrometry-based protein footprinting for higher-order structure analysis: fundamentals and applications

XR Liu, MM Zhang, ML Gross - Chemical reviews, 2020 - ACS Publications
Proteins adopt different higher-order structures (HOS) to enable their unique biological
functions. Understanding the complexities of protein higher-order structures and dynamics …

ChemOS: An orchestration software to democratize autonomous discovery

LM Roch, F Häse, A Aspuru-Guzik - 2020 - books.rsc.org
The key economic and societal challenges of the 21st century, including clean energy,
global health and sustainability, 1 require the scientific discovery process to be streamlined …

New insights into the pH dependence of anthocyanin-protein interactions by a case study of cyanidin-3-O-glucoside and bovine serum albumin

P Yang, W Wang, Z Xu, L Rao, L Zhao, Y Wang… - Food …, 2023 - Elsevier
Anthocyanins are natural pigments that can undergo structural transformations depending
on pH, and their interactions with proteins have received considerable attention in recent …

Formation of nanocomplexes comprising whey proteins and fucoxanthin: Characterization, spectroscopic analysis, and molecular docking

J Zhu, X Sun, S Wang, Y Xu, D Wang - Food Hydrocolloids, 2017 - Elsevier
Fully elucidating the protein-ligand interaction mechanisms can help us better construct the
nanocarrier to delivery fucoxanthin. Thus, in this study, the complexes comprising …

Quality assessment and optimization of purified protein samples: why and how?

B Raynal, P Lenormand, B Baron, S Hoos… - Microbial cell …, 2014 - Springer
Purified protein quality control is the final and critical check-point of any protein production
process. Unfortunately, it is too often overlooked and performed hastily, resulting in …

[HTML][HTML] Protein corona–from molecular adsorption to physiological complexity

L Treuel, D Docter, M Maskos… - Beilstein journal of …, 2015 - beilstein-journals.org
In biological environments, nanoparticles are enshrouded by a layer of biomolecules,
predominantly proteins, mediating its subsequent interactions with cells. Detecting this …

MD–ligand–receptor: a high-performance computing tool for characterizing ligand–receptor binding interactions in molecular dynamics trajectories

M Pieroni, F Madeddu, J Di Martino, M Arcieri… - International Journal of …, 2023 - mdpi.com
Molecular dynamics simulation is a widely employed computational technique for studying
the dynamic behavior of molecular systems over time. By simulating macromolecular …

Toward a molecular understanding of nanoparticle–protein interactions

L Treuel, GU Nienhaus - Biophysical reviews, 2012 - Springer
Wherever nanoparticles (NPs) come in contact with a living organism, physical and chemical
interactions take place between the surfaces of the NPs and biomatter, in particular proteins …

Examining the Electrochemical Properties of Hybrid Aqueous/Ionic Liquid Solid Polymer Electrolytes through the Lens of Composition‐Function Relationships

KB Ludwig, R Correll‐Brown, M Freidlin… - Advanced Energy …, 2023 - Wiley Online Library
Solid polymer electrolytes (SPEs) have the potential to meet evolving Li‐ion battery
demands, but for these electrolytes to satisfy growing power and energy density …