Tutorial: practical considerations for tissue clearing and imaging
Tissue clearing has become a powerful technique for studying anatomy and morphology at
scales ranging from entire organisms to subcellular features. With the recent proliferation of …
scales ranging from entire organisms to subcellular features. With the recent proliferation of …
Inhibition of arginase modulates T-cell response in the tumor microenvironment of lung carcinoma
A Sosnowska, J Chlebowska-Tuz, P Matryba… - …, 2021 - Taylor & Francis
Immunotherapy has demonstrated significant activity in a broad range of cancer types, but
still the majority of patients receiving it do not maintain durable therapeutic responses …
still the majority of patients receiving it do not maintain durable therapeutic responses …
Perspective: extending the utility of three-dimensional organoids by tissue clearing technologies
An organoid, a self-organizing organ-like tissue developed from stem cells, can exhibit a
miniaturized three-dimensional (3D) structure and part of the physiological functions of the …
miniaturized three-dimensional (3D) structure and part of the physiological functions of the …
A 3D analysis of cleared human melanoma
Cutaneous melanoma is one of the most aggressive and deadliest cancers in human beings
due to its invasiveness and other factors. Histopathological analysis is crucial for a proper …
due to its invasiveness and other factors. Histopathological analysis is crucial for a proper …
Tissue optical clearing and expanding solution for improved nuclear segmentation
P Matryba, A Wolny, A Chwastowicz, J Tomczuk… - View, 2025 - Wiley Online Library
Over the recent years, fluorescence microscopy has seen substantial progress, transitioning
from primarily qualitative analysis to a profoundly quantitative methodology, yet limitations in …
from primarily qualitative analysis to a profoundly quantitative methodology, yet limitations in …
A simple and effective vascular network labeling method for transparent tissues of mice
L Bai, Y Wu, W Dai, J Zhang, L Zheng… - Journal of …, 2023 - Wiley Online Library
Vascular network labeling in transparent tissues provides more complete information on
blood vessels. To achieve a fast and efficient method for vascular network labeling in …
blood vessels. To achieve a fast and efficient method for vascular network labeling in …
[HTML][HTML] Imaging of fluorescent polymer dots in relation to channels and immune cells in the lymphatic system
Y Zhang, J Zhang, X Li, J Li, S Lu, Y Li, P Ren… - Materials Today Bio, 2022 - Elsevier
Polymer dots (Pdots) have been applied to imaging lymph nodes (LNs) and lymphatic
vessels (LVs) in living mice and rats. However, the mechanism of absorption, distribution …
vessels (LVs) in living mice and rats. However, the mechanism of absorption, distribution …
Challenges and opportunities in hydrophilic tissue clearing methods
Hydrophilic tissue clearing protocols represent one of the major categories of recently
emerging optical tissue clearing methods. For over 20 years, researchers have tested many …
emerging optical tissue clearing methods. For over 20 years, researchers have tested many …
Semi-automated protocol to quantify and characterize fluorescent three-dimensional vascular images
The microvasculature facilitates gas exchange, provides nutrients to cells, and regulates
blood flow in response to stimuli. Vascular abnormalities are an indicator of pathology for …
blood flow in response to stimuli. Vascular abnormalities are an indicator of pathology for …
Semi-automated protocol to quantify and characterize fluorescent, 3D vascular images
The microvasculature facilitates gas exchange, provides nutrients to cells, and regulates
blood flow in response to stimuli. Vascular abnormalities are an indicator of pathology for …
blood flow in response to stimuli. Vascular abnormalities are an indicator of pathology for …