Constraint-based modeling (CBM) has evolved as the core systems biology tool to map the
interrelations between genotype, phenotype, and external environment. The recent …

Gene Expression is the process of determining the physical characteristics of living beings
by generating the necessary proteins. Gene Expression takes place in two steps, translation …

Alzheimer's disease is a genetically complex disorder, and microarray technology provides
valuable insights into it. However, the high dimensionality of microarray datasets and small …

OBJECTIVE: Suitable techniques for microarray analysis have been widely researched,
particularly for the study of marker genes expressed to a specific type of cancer. Most of the …

The field of gene expression data analysis has grown in the past few years from being
purely data-centric to integrative, aiming at complementing microarray analysis with data …

Background In recent years, to investigate challenging bioinformatics problems, the
utilization of multiple genomic and proteomic sources has become immensely popular …

Accumulating evidence shows that clinical factors alone are not adequate for predicting the
survival of patients with ovarian cancer (OvCa), and many genes have been found to be …

Oral epithelial dysplasia (OED) often precedes oral cancer. Understanding the underlying
complex biological aspects of dysplasia associated oral carcinogenesis using important …

We propose a methodology for predictive classification from gene expression data, able to
combine the robustness of highdimensional statistical classification methods with the …

With the advance of gene expression data in the bioinformatics field, the questions which
frequently arise, for both computer and medical scientists, are which genes are significantly …