Highlights•Chloroquine is used for anti-malaria, anti-cancer and anti-virus treatment.•The
efficacy of hydroxychloroquine against COVID-19 is controversial.•Several quinoline …

Intensified treatment and control efforts since the early 2000s have dramatically reduced the
burden of Plasmodium falciparum malaria. However, drug resistance threatens to derail this …

Malaria parasites break down host haemoglobin into peptides and amino acids in the
digestive vacuole for export to the parasite cytoplasm for growth: interrupting this process is …

Recent studies into the global causes of severe diarrhoea in young children have identified
the protozoan parasite Cryptosporidium as the second most important diarrhoeal pathogen …

Antimalarial chemotherapy, globally reliant on artemisinin-based combination therapies
(ACTs), is threatened by the spread of drug resistance in Plasmodium falciparum parasites …

Successful establishment of CRISPR/Cas9 genome editing technology in Plasmodium spp.
has provided a powerful tool to transform Plasmodium falciparum into a genetically more …

Malaria is the most deadly parasitic disease, affecting hundreds of millions of people
worldwide. Malaria parasites have been associated with their hosts for millions of years …

Recent years have seen a lot of interest in transition metal carbides/carbonitrides (MXenes),
Which is one of newly proliferating two-dimensional (2D) materials. The advantages and …

It is over 100 years since the life-cycle of the malaria parasite Plasmodium was discovered,
yet its intricacies remain incompletely understood-a knowledge gap that may prove crucial …

CRISPR/Cas9-based genome editing has yet to be reported in species of the
Platyhelminthes. We tested this approach by targeting omega-1 (ω1) of Schistosoma …