Significance: Mitochondria are the cellular energy-producing organelles and are at the
crossroad of determining cell life and death. As such, the function of mitochondria has been …

While physical activity represents a key element in the prevention and management of many
chronic diseases, we and others believe that physical inactivity is a primary cause of obesity …

BACKGROUND & AIMS: In this study, we sought to determine the temporal relationship
between hepatic mitochondrial dysfunction, hepatic steatosis and insulin resistance, and to …

Exercise training is commonly prescribed for treatment of nonalcoholic fatty liver disease
(NAFLD). We sought to determine whether exercise training prevents the development of …

The maintenance of normal body weight either through dietary modification or being
habitually more physically active is associated with reduced incidence of nonalcoholic fatty …

Accumulating evidence indicates integration of dopamine function with metabolic signals,
highlighting a potential role for dopamine in energy balance, frequently construed as …

Roux-en-Y gastric bypass surgery (GBS) is the most effective treatment for morbid obesity.
GBS is a restrictive malabsorptive procedure, but many patients also report altered taste …

Modern animal breeding programs are largely based on biotechnological procedures,
including AI and embryo transfer technology. Recent breakthroughs in reproductive …

Here, we sought to compare the efficacy of combining exercise and metformin for the
treatment of type 2 diabetes and nonalcoholic fatty liver disease (NAFLD) in hyperphagic …

Enteroendocrine cells (EEC) form the basis of the largest endocrine system in the body.
They secrete multiple regulatory molecules which control physiological and homeostatic …