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The role of iron and reactive oxygen species in cell death
The transition metal iron is essential for life, yet potentially toxic iron-catalyzed reactive
oxygen species (ROS) are unavoidable in an oxygen-rich environment. Iron and ROS are …
oxygen species (ROS) are unavoidable in an oxygen-rich environment. Iron and ROS are …
Ischemia-triggered glutamate excitotoxicity from the perspective of glial cells
A plethora of neurological disorders shares a final common deadly pathway known as
excitotoxicity. Among these disorders, ischemic injury is a prominent cause of death and …
excitotoxicity. Among these disorders, ischemic injury is a prominent cause of death and …
Ferrostatins inhibit oxidative lipid damage and cell death in diverse disease models
Ferrostatin-1 (Fer-1) inhibits ferroptosis, a form of regulated, oxidative, nonapoptotic cell
death. We found that Fer-1 inhibited cell death in cellular models of Huntington's disease …
death. We found that Fer-1 inhibited cell death in cellular models of Huntington's disease …
Cognitive outcomes of children born extremely or very preterm since the 1990s and associated risk factors: a meta-analysis and meta-regression
Importance Despite apparent progress in perinatal care, children born extremely or very
preterm (EP/VP) remain at high risk for cognitive deficits. Insight into factors contributing to …
preterm (EP/VP) remain at high risk for cognitive deficits. Insight into factors contributing to …
Ferroptosis and its role in diverse brain diseases
Ferroptosis is a recently identified, iron-regulated, non-apoptotic form of cell death. It is
characterized by cellular accumulation of lipid reactive oxygen species that ultimately leads …
characterized by cellular accumulation of lipid reactive oxygen species that ultimately leads …
E van Tilborg, CGM de Theije, M van Hal, N Wagenaar… - Glia, 2018 - Wiley Online Library
Infants born prematurely are at high risk to develop white matter injury (WMI), due to
exposure to hypoxic and/or inflammatory insults. Such perinatal insults negatively impact the …
exposure to hypoxic and/or inflammatory insults. Such perinatal insults negatively impact the …
New MR imaging assessment tool to define brain abnormalities in very preterm infants at term
H Kidokoro, JJ Neil, TE Inder - American Journal of Neuroradiology, 2013 - ajnr.org
BACKGROUND AND PURPOSE: WM injury is the dominant form of injury in preterm infants.
However, other cerebral structures, including the deep gray matter and the cerebellum, can …
However, other cerebral structures, including the deep gray matter and the cerebellum, can …
Influence of infection during pregnancy on fetal development
KMA Waldorf, RM McAdams - Reproduction, 2013 - rep.bioscientifica.com
Infection by bacteria, viruses, and parasites may lead to fetal death, organ injury, or limited
sequelae depending on the pathogen. Here, we consider the role of infection during …
sequelae depending on the pathogen. Here, we consider the role of infection during …