Insulin resistance in depression: A large meta-analysis of metabolic parameters and variation

BS Fernandes, E Salagre, N Enduru, I Grande… - Neuroscience & …, 2022 - Elsevier
Increased insulin resistance is recognized in psychiatric disorders, such as schizophrenia
and bipolar disorder, but its occurrence in depression is less clear. Our aims were to verify if …

Improving functioning, quality of life, and well-being in patients with bipolar disorder

CM Bonnín, M Reinares, A Martínez-Arán… - International Journal …, 2019 - academic.oup.com
People with bipolar disorder frequently experience persistent residual symptoms, problems
in psychosocial functioning, cognitive impairment, and poor quality of life. In the last decade …

Preventive psychiatry: a blueprint for improving the mental health of young people

P Fusar‐Poli, CU Correll, C Arango, M Berk… - World …, 2021 - Wiley Online Library
Preventive approaches have latterly gained traction for improving mental health in young
people. In this paper, we first appraise the conceptual foundations of preventive psychiatry …

What we learn about bipolar disorder from large‐scale neuroimaging: Findings and future directions from the ENIGMA Bipolar Disorder Working Group

CRK Ching, DP Hibar, TP Gurholt, A Nunes… - Human brain …, 2022 - Wiley Online Library
MRI‐derived brain measures offer a link between genes, the environment and behavior and
have been widely studied in bipolar disorder (BD). However, many neuroimaging studies of …

The use of machine learning techniques in trauma-related disorders: a systematic review

LF Ramos-Lima, V Waikamp… - Journal of psychiatric …, 2020 - Elsevier
Establishing the diagnosis of trauma-related disorders such as Acute Stress Disorder (ASD)
and Posttraumatic Stress Disorder (PTSD) have always been a challenge in clinical practice …

Closing the gap for children with OCD: a staged-care model of cognitive behavioural therapy with exposure and response prevention

LJ Farrell, AM Waters, EA Storch, G Simcock… - Clinical Child and …, 2023 - Springer
Childhood obsessive–compulsive disorder (OCD) is among the most prevalent and
disabling mental health conditions affecting children and adolescents. Although the distress …

[HTML][HTML] Pharmacogenomics: A road ahead for precision medicine in psychiatry

AF Pardiñas, MJ Owen, JTR Walters - Neuron, 2021 - cell.com
Psychiatric genomics is providing insights into the nature of psychiatric conditions that in
time should identify new drug targets and improve patient care. Less attention has been paid …

Sleep disturbance in bipolar disorder: neuroglia and circadian rhythms

L Steardo Jr, R De Filippis, EA Carbone… - Frontiers in …, 2019 - frontiersin.org
The worldwide prevalence of sleep disorders is approximately 50%, with an even higher
occurrence in a psychiatric population. Bipolar disorder (BD) is a severe mental illness …

Dissecting clinical heterogeneity of bipolar disorder using multiple polygenic risk scores

BJ Coombes, M Markota, JJ Mann, C Colby… - Translational …, 2020 - nature.com
Bipolar disorder (BD) has high clinical heterogeneity, frequent psychiatric comorbidities, and
elevated suicide risk. To determine genetic differences between common clinical sub …

Barriers to genetic testing in clinical psychiatry and ways to overcome them: from clinicians' attitudes to sociocultural differences between patients across the globe

J Pinzón-Espinosa, M van der Horst, J Zinkstok… - Translational …, 2022 - nature.com
Genetic testing has evolved rapidly over recent years and new developments have the
potential to provide insights that could improve the ability to diagnose, treat, and prevent …