In vivo delivery, pharmacokinetics, biodistribution and toxicity of iron oxide nanoparticles

H Arami, A Khandhar, D Liggitt… - Chemical Society …, 2015 - pubs.rsc.org
Iron oxide nanoparticles (IONPs) have been extensively used during the last two decades,
either as effective bio-imaging contrast agents or as carriers of biomolecules such as drugs …

Pharmacokinetics of magnetic iron oxide nanoparticles for medical applications

J Nowak-Jary, B Machnicka - Journal of Nanobiotechnology, 2022 - Springer
Magnetic iron oxide nanoparticles (MNPs) have been under intense investigation for at least
the last five decades as they show enormous potential for many biomedical applications …

Recent advances in superparamagnetic iron oxide nanoparticles (SPIONs) for in vitro and in vivo cancer nanotheranostics

G Kandasamy, D Maity - International journal of pharmaceutics, 2015 - Elsevier
Recently superparamagnetic iron oxide nanoparticles (SPIONs) have been extensively used
in cancer therapy and diagnosis (theranostics) via magnetic targeting, magnetic resonance …

In vivo biodistribution and clearance of magnetic iron oxide nanoparticles for medical applications

J Nowak-Jary, B Machnicka - International Journal of …, 2023 - Taylor & Francis
Magnetic iron oxide nanoparticles (magnetite and maghemite) are intensively studied due to
their broad potential applications in medical and biological sciences. Their unique …

Radiolabeling nanomaterials for multimodality imaging: New insights into nuclear medicine and cancer diagnosis

J Ge, Q Zhang, J Zeng, Z Gu, M Gao - Biomaterials, 2020 - Elsevier
Nuclear medicine imaging has been developed as a powerful diagnostic approach for
cancers by detecting gamma rays directly or indirectly from radionuclides to construct …

In Vitro/In Vivo Toxicity Evaluation and Quantification of Iron Oxide Nanoparticles

US Patil, S Adireddy, A Jaiswal, S Mandava… - International journal of …, 2015 - mdpi.com
Increasing biomedical applications of iron oxide nanoparticles (IONPs) in academic and
commercial settings have alarmed the scientific community about the safety and assessment …

Positron emission tomography and nanotechnology: A dynamic duo for cancer theranostics

S Goel, CG England, F Chen, W Cai - Advanced drug delivery reviews, 2017 - Elsevier
Abstract Development of novel imaging probes for cancer diagnosis is critical for early
disease detection and management. The past two decades have witnessed a surge in the …

Use of superparamagnetic iron oxide nanoparticles (SPIONs) via multiple imaging modalities and modifications to reduce cytotoxicity: An educational review

NR Nelson, JD Port, MK Pandey - Journal of Nanotheranostics, 2020 - mdpi.com
The aim of the present educational review on superparamagnetic iron oxide nanoparticles
(SPIONs) is to inform and guide young scientists and students about the potential use and …

Trastuzumab Conjugated Superparamagnetic Iron Oxide Nanoparticles Labeled with 225Ac as a Perspective Tool for Combined α-Radioimmunotherapy and …

E Cędrowska, M Pruszyński, W Gawęda, M Żuk… - Molecules, 2020 - mdpi.com
It has been proven and confirmed in numerous repeated tests, that the use of a combination
of several therapeutic methods gives much better treatment results than in the case of …

Imaging constructs: the rise of iron oxide nanoparticles

BEB Crețu, G Dodi, A Shavandi, I Gardikiotis… - Molecules, 2021 - mdpi.com
Over the last decade, an important challenge in nanomedicine imaging has been the work to
design multifunctional agents that can be detected by single and/or multimodal techniques …