Pathophysiology and probable etiology of cerebral small vessel disease in vascular dementia and Alzheimer's disease
Vascular cognitive impairment and dementia (VCID) is commonly caused by vascular
injuries in cerebral large and small vessels and is a key driver of age-related cognitive …
injuries in cerebral large and small vessels and is a key driver of age-related cognitive …
Cerebral microvascular complications of type 2 diabetes: stroke, cognitive dysfunction, and depression
Adults with type 2 diabetes are at an increased risk of develo** certain brain or mental
disorders, including stroke, dementia, and depression. Although these disorders are not …
disorders, including stroke, dementia, and depression. Although these disorders are not …
[HTML][HTML] Emerging concepts in vascular dementia: a review
SC Bir, MW Khan, V Javalkar, EG Toledo… - Journal of Stroke and …, 2021 - Elsevier
Abstract Objective Vascular dementia (VaD) is the second most common cause of dementia
and a major health concern worldwide. A comprehensive review on VaD is warranted for …
and a major health concern worldwide. A comprehensive review on VaD is warranted for …
Genetics of common cerebral small vessel disease
Cerebral small vessel disease (cSVD) is a leading cause of ischaemic and haemorrhagic
stroke and a major contributor to dementia. Covert cSVD, which is detectable with brain MRI …
stroke and a major contributor to dementia. Covert cSVD, which is detectable with brain MRI …
Stroke genetics: discovery, biology, and clinical applications
Stroke, a leading cause of long-term disability and death worldwide, has a heritable
component. Recent gene discovery efforts have expanded the number of known single …
component. Recent gene discovery efforts have expanded the number of known single …
Cardiovascular comorbidities, inflammation, and cerebral small vessel disease
LE Evans, JL Taylor, CJ Smith… - Cardiovascular …, 2021 - academic.oup.com
Cerebral small vessel disease (cSVD) is the most common cause of vascular cognitive
impairment and affects all levels of the brain's vasculature. Features include diverse …
impairment and affects all levels of the brain's vasculature. Features include diverse …
Risk factors for cognitive impairment and dementia after stroke: a systematic review and meta-analysis
Background Cognitive impairment and dementia are highly prevalent among stroke
survivors and represent a major burden for patients, carers, and health-care systems. We …
survivors and represent a major burden for patients, carers, and health-care systems. We …
Genetics insights in the relationship between type 2 diabetes and coronary heart disease
MO Goodarzi, JI Rotter - Circulation research, 2020 - Am Heart Assoc
Diabetes mellitus is a major risk factor for coronary heart disease (CHD). The major form of
diabetes mellitus is type 2 diabetes mellitus (T2D), which is thus largely responsible for the …
diabetes mellitus is type 2 diabetes mellitus (T2D), which is thus largely responsible for the …
Diabetes mellitus, glycemic traits, and cerebrovascular disease: a Mendelian randomization study
Objective We employed Mendelian randomization to explore the effects of genetic
predisposition to type 2 diabetes (T2D), hyperglycemia, insulin resistance, and pancreatic β …
predisposition to type 2 diabetes (T2D), hyperglycemia, insulin resistance, and pancreatic β …
Relationship between type 2 diabetes and white matter hyperintensity: a systematic review
DQ Wang, L Wang, MM Wei, XS **a, XL Tian… - Frontiers in …, 2020 - frontiersin.org
White matter (WM) disease is recognized as an important cause of cognitive decline and
dementia. White matter lesions (WMLs) appear as white matter hyperintensities (WMH) on …
dementia. White matter lesions (WMLs) appear as white matter hyperintensities (WMH) on …