Creutzfeldt–Jakob disease (CJD) is a rapidly progressive, fatal and transmissible
neurodegenerative disease associated with the accumulation of misfolded prion protein in …

Transmissible spongiform encephalopathies (TSEs) are inevitably lethal neurodegenerative
diseases that affect humans and a large variety of animals. The infectious agent responsible …

Obesity results from chronic energy surplus and excess lipid storage in white adipose tissue
(WAT). In contrast, brown adipose tissue (BAT) efficiently burns lipids through adaptive …

A naturally occurring transmissible spongiform encephalopathy (TSE) of mule deer was first
reported in Colorado and Wyoming in 1967 and has since spread to other members of the …

Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy (TSE) that
affects members of the cervidae family. The infectious agent is a misfolded isoform (PrPSC) …

Prions cause infectious and fatal neurodegenerative diseases in mammals. Chronic wasting
disease (CWD), a prion disease of cervids, spreads efficiently among wild and farmed …

Objective To report a novel prion disease characterized by distinct histopathological and
immunostaining features, and associated with an abnormal isoform of the prion protein (PrP) …

Objective: The objective of the study is to report 2 new genotypic forms of protease‐sensitive
prionopathy (PSPr), a novel prion disease described in 2008, in 11 subjects all homozygous …

Creutzfeldt-Jakob disease (CJD) is a degenerative neurologic disorder of humans with an
incidence in the United States of approximately 1 case per million population per year. 1" 3 …

Prions are infectious proteins composed of the abnormal disease-causing isoform PrPSc,
which induces conformational conversion of the host-encoded normal cellular prion protein …