SARS-CoV-2: structure, biology, and structure-based therapeutics development
MY Wang, R Zhao, LJ Gao, XF Gao… - Frontiers in cellular …, 2020 - frontiersin.org
The pandemic of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
has been posing great threats to the world in many aspects. Effective therapeutic and …
has been posing great threats to the world in many aspects. Effective therapeutic and …
The glycosylation in SARS-CoV-2 and its receptor ACE2
Y Gong, S Qin, L Dai, Z Tian - Signal Transduction and Targeted …, 2021 - nature.com
Abstract Coronavirus disease 2019 (COVID-19), a highly infectious disease caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected more than …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected more than …
Effectiveness of Covid-19 vaccines against the B. 1.617. 2 (Delta) variant
Abstract Background The B. 1.617. 2 (delta) variant of the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (Covid-19) …
coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (Covid-19) …
[HTML][HTML] Spike mutation D614G alters SARS-CoV-2 fitness
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein
substitution D614G became dominant during the coronavirus disease 2019 (COVID-19) …
substitution D614G became dominant during the coronavirus disease 2019 (COVID-19) …
Mutations in SARS-CoV-2 variants of concern link to increased spike cleavage and virus transmission
SARS-CoV-2 lineages have diverged into highly prevalent variants termed" variants of
concern"(VOCs). Here, we characterized emerging SARS-CoV-2 spike polymorphisms in …
concern"(VOCs). Here, we characterized emerging SARS-CoV-2 spike polymorphisms in …
[HTML][HTML] Orthogonal SARS-CoV-2 serological assays enable surveillance of low-prevalence communities and reveal durable humoral immunity
We conducted a serological study to define correlates of immunity against SARS-CoV-2.
Compared to those with mild coronavirus disease 2019 (COVID-19) cases, individuals with …
Compared to those with mild coronavirus disease 2019 (COVID-19) cases, individuals with …
[HTML][HTML] D614G mutation alters SARS-CoV-2 spike conformation and enhances protease cleavage at the S1/S2 junction
The severe acute respiratory coronavirus 2 (SARS-CoV-2) spike (S) protein is the target of
vaccine design efforts to end the coronavirus disease 2019 (COVID-19) pandemic. Despite …
vaccine design efforts to end the coronavirus disease 2019 (COVID-19) pandemic. Despite …
SARS-CoV-2 tropism, entry, replication, and propagation: Considerations for drug discovery and development
Coronaviruses, named for their crown-like spiked surface, are genetically diverse and can
infect multiple animal species, including bats, pigs, cats, rodents, and humans. Aside from …
infect multiple animal species, including bats, pigs, cats, rodents, and humans. Aside from …
A plasmid DNA-launched SARS-CoV-2 reverse genetics system and coronavirus toolkit for COVID-19 research
The recent emergence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-
2), the underlying cause of Coronavirus Disease 2019 (COVID-19), has led to a worldwide …
2), the underlying cause of Coronavirus Disease 2019 (COVID-19), has led to a worldwide …
[HTML][HTML] The antigenic anatomy of SARS-CoV-2 receptor binding domain
Antibodies are crucial to immune protection against SARS-CoV-2, with some in emergency
use as therapeutics. Here, we identify 377 human monoclonal antibodies (mAbs) …
use as therapeutics. Here, we identify 377 human monoclonal antibodies (mAbs) …