Current therapies for multiple sclerosis (MS) reduce both relapses and relapse-associated
worsening of disability, which is assumed to be mainly associated with transient infiltration of …

Multiple sclerosis (MS) is a chronic inflammatory, demyelinating and neurodegenerative
disease affecting the central nervous system (CNS), often characterized by the accumulation …

The treatment of multiple sclerosis (MS), the most common chronic inflammatory,
demyelinating and neurodegenerative disease of the central nervous system (CNS) …

Brain imaging is increasingly used to support clinicians in diagnosing multiple sclerosis
(MS) and monitoring its progression. However, the role of magnetic resonance imaging …

Leptomeningeal inflammation in multiple sclerosis is associated with worse clinical
outcomes and greater cortical pathology. Despite progress in identifying this process in …

Acquired demyelinating diseases of the central nervous system (CNS) comprise
inflammatory conditions, including multiple sclerosis (MS) and related diseases, as well as …

Background The lack of systematic evidence on leptomeningeal enhancement (LME) on
MRI in neurological diseases, including multiple sclerosis (MS), hampers its interpretation in …

Multiple sclerosis is a chronic autoimmune disease of the central nervous system that results
in varying degrees of disability. Progressive multiple sclerosis, characterized by a steady …

Autoimmune encephalitis (AE) comprises a heterogeneous group of disorders in which the
host immune system targets self-antigens expressed in the central nervous system. The …

The brain is protected by the endothelial blood–brain barrier (BBB) that limits the access of
micro‐organisms, tumour cells, immune cells and autoantibodies to the parenchyma …