Computation through neural population dynamics

S Vyas, MD Golub, D Sussillo… - Annual review of …, 2020 - annualreviews.org
Significant experimental, computational, and theoretical work has identified rich structure
within the coordinated activity of interconnected neural populations. An emerging challenge …

Neural manifolds for the control of movement

JA Gallego, MG Perich, LE Miller, SA Solla - Neuron, 2017 - cell.com
The analysis of neural dynamics in several brain cortices has consistently uncovered low-
dimensional manifolds that capture a significant fraction of neural variability. These neural …

Long-term stability of cortical population dynamics underlying consistent behavior

JA Gallego, MG Perich, RH Chowdhury, SA Solla… - Nature …, 2020 - nature.com
Animals readily execute learned behaviors in a consistent manner over long periods of time,
and yet no equally stable neural correlate has been demonstrated. How does the cortex …

Brain-machine interfaces: from basic science to neuroprostheses and neurorehabilitation

MA Lebedev, MAL Nicolelis - Physiological reviews, 2017 - journals.physiology.org
Brain-machine interfaces (BMIs) combine methods, approaches, and concepts derived from
neurophysiology, computer science, and engineering in an effort to establish real-time …

Cortical pattern generation during dexterous movement is input-driven

BA Sauerbrei, JZ Guo, JD Cohen, M Mischiati, W Guo… - Nature, 2020 - nature.com
The motor cortex controls skilled arm movement by sending temporal patterns of activity to
lower motor centres. Local cortical dynamics are thought to shape these patterns throughout …

Waking state: rapid variations modulate neural and behavioral responses

MJ McGinley, M Vinck, J Reimer, R Batista-Brito… - Neuron, 2015 - cell.com
The state of the brain and body constantly varies on rapid and slow timescales. These
variations contribute to the apparent noisiness of sensory responses at both the neural and …

Cortical population activity within a preserved neural manifold underlies multiple motor behaviors

JA Gallego, MG Perich, SN Naufel, C Ethier… - Nature …, 2018 - nature.com
Populations of cortical neurons flexibly perform different functions; for the primary motor
cortex (M1) this means a rich repertoire of motor behaviors. We investigate the flexibility of …

Decoding motor imagery from the posterior parietal cortex of a tetraplegic human

T Aflalo, S Kellis, C Klaes, B Lee, Y Shi, K Pejsa… - Science, 2015 - science.org
Nonhuman primate and human studies have suggested that populations of neurons in the
posterior parietal cortex (PPC) may represent high-level aspects of action planning that can …

Neuroprosthetics: from sensorimotor to cognitive disorders

A Gupta, N Vardalakis, FB Wagner - Communications biology, 2023 - nature.com
Neuroprosthetics is a multidisciplinary field at the interface between neurosciences and
biomedical engineering, which aims at replacing or modulating parts of the nervous system …

The proprioceptive senses: their roles in signaling body shape, body position and movement, and muscle force

U Proske, SC Gandevia - Physiological reviews, 2012 - journals.physiology.org
This is a review of the proprioceptive senses generated as a result of our own actions. They
include the senses of position and movement of our limbs and trunk, the sense of effort, the …