Xenobiotic responses in insects

L Gao, H Qiao, P Wei, B Moussian… - Archives of Insect …, 2022 - Wiley Online Library
Insects have evolved a powerful detoxification system to protect themselves against
environmental and anthropogenic xenobiotics including pesticides and nanoparticles. The …

Canalization and robustness in human genetics and disease

G Gibson, KA Lacek - Annual Review of Genetics, 2020 - annualreviews.org
Canalization refers to the evolution of populations such that the number of individuals who
deviate from the optimum trait, or experience disease, is minimized. In the presence of rapid …

A Population Genomic Assessment of Three Decades of Evolution in a Natural Drosophila Population

JD Lange, H Bastide, JB Lack… - Molecular Biology and …, 2022 - academic.oup.com
Population genetics seeks to illuminate the forces sha** genetic variation, often based on
a single snapshot of genomic variation. However, utilizing multiple sampling times to study …

Polygenicity and Epistasis Underlie Fitness-Proximal Traits in the Caenorhabditis elegans Multiparental Experimental Evolution (CeMEE) Panel

LM Noble, I Chelo, T Guzella, B Afonso, DD Riccardi… - Genetics, 2017 - academic.oup.com
Using a new experimentally evolved multiparent map** resource for C. elegans, Noble et
al. have outlined the genetic architecture of worm fertility.. Understanding the genetic basis …

Determinants of QTL map** power in the realized collaborative cross

GR Keele, WL Crouse, SNP Kelada… - G3: Genes, Genomes …, 2019 - academic.oup.com
Abstract The Collaborative Cross (CC) is a mouse genetic reference population whose
range of applications includes quantitative trait loci (QTL) map**. The design of a CC QTL …

Phenotypic responses to and genetic architecture of sterility following exposure to sub-lethal temperature during development

MK Zwoinska, LR Rodrigues, J Slate… - Frontiers in Genetics, 2020 - frontiersin.org
Thermal tolerance range, based on temperatures that result in incapacitating effects,
influences species' distributions and has been used to predict species' response to …

[HTML][HTML] The genome sequence of the Neotropical brown stink bug, Euschistus heros provides insights into population structure, demographic history and signatures …

KS Singh, EMG Cordeiro, BJ Hunt, AA Pandit… - Insect Biochemistry and …, 2023 - Elsevier
The Neotropical brown stink bug, Euschistus heros, is a major pest of soybean in South
America. The importance of E. heros as a pest has grown significantly in recent times due to …

Genomic and transcriptomic analyses in Drosophila suggest that the ecdysteroid kinase-like (EcKL) gene family encodes the 'detoxification-by-phosphorylation' …

JL Scanlan, RS Gledhill-Smith, P Battlay… - Insect Biochemistry and …, 2020 - Elsevier
Phosphorylation is a phase II detoxification reaction that, among animals, occurs near
exclusively in insects, but the enzymes responsible have never been cloned or otherwise …

Shared genomic regions underlie natural variation in diverse toxin responses

KS Evans, SC Brady, JS Bloom, RE Tanny, DE Cook… - Genetics, 2018 - academic.oup.com
Phenotypic complexity is caused by the contributions of environmental factors and multiple
genetic loci, interacting or acting independently. Studies of yeast and Arabidopsis often find …

Gene expression variation underlying tissue-specific responses to copper stress in Drosophila melanogaster

ER Everman, SJ Macdonald - G3: Genes, Genomes, Genetics, 2024 - academic.oup.com
Copper is one of a handful of biologically necessary heavy metals that is also a common
environmental pollutant. Under normal conditions, copper ions are required for many key …