Abstract The interleukin-1 (IL-1) family is one of the first described cytokine families and
consists of eight cytokines (IL-1β, IL-1α, IL-18, IL-33, IL-36α, IL-36β, IL-36γ and IL-37) and …

Hyperlipidemia is confirmed to be associated with several health problems that include the
combination of diabetes mellitus, obesity, and hypertension, ie, metabolic syndrome …

Interactions between regulatory elements are of crucial importance for the understanding of
transcriptional regulation and the interpretation of disease mechanisms. Hi-C technique has …

Heat shock proteins (HSPs) are molecular chaperones with critical roles in the maintenance
of cellular proteostasis. HSPs, which regulate protein folding and refolding, assembly …

This review examines the role of interleukin (IL)-38 in health and disease. IL-38 functions as
an anti-inflammatory cytokine in the IL-1 family, with properties comparable to IL-37, another …

IL-38 is the most recently discovered cytokine of the IL-1 family and is considered a potential
inhibitor of the IL-1 and Toll-like receptor families. IL-38 exerts anti-inflammatory properties …

Macrophages play an important role in clearing necrotic myocardial tissues, myocardial
ischemia–reperfusion injury, and ventricular remodeling after myocardial infarction. M1 …

Excessive immune‐mediated inflammatory reaction plays a deleterious role in ventricular
remodelling after myocardial infarction (MI). Interleukin (IL)‐38 is a newly characterized …

The natural history of heart failure (HF) is not linear, because changes in the heart structure
and function start long before the disease becomes clinically evident. Many different …

Objective. Recent studies suggest that IL‐38 is associated with autoimmune diseases.
Furthermore, IL‐38 is expressed in human atheromatous plaque. However, the plasma …