Human genetic and immunological determinants of critical COVID-19 pneumonia
SARS-CoV-2 infection is benign in most individuals but, in around 10% of cases, it triggers
hypoxaemic COVID-19 pneumonia, which leads to critical illness in around 3% of cases …
hypoxaemic COVID-19 pneumonia, which leads to critical illness in around 3% of cases …
Immunological mechanisms of vaccine-induced protection against COVID-19 in humans
Most COVID-19 vaccines are designed to elicit immune responses, ideally neutralizing
antibodies (NAbs), against the SARS-CoV-2 spike protein. Several vaccines, including …
antibodies (NAbs), against the SARS-CoV-2 spike protein. Several vaccines, including …
FcγR-mediated SARS-CoV-2 infection of monocytes activates inflammation
SARS-CoV-2 can cause acute respiratory distress and death in some patients. Although
severe COVID-19 is linked to substantial inflammation, how SARS-CoV-2 triggers …
severe COVID-19 is linked to substantial inflammation, how SARS-CoV-2 triggers …
The cGAS–STING pathway drives type I IFN immunopathology in COVID-19
COVID-19, which is caused by infection with SARS-CoV-2, is characterized by lung
pathology and extrapulmonary complications,. Type I interferons (IFNs) have an essential …
pathology and extrapulmonary complications,. Type I interferons (IFNs) have an essential …
The signal pathways and treatment of cytokine storm in COVID-19
L Yang, X **e, Z Tu, J Fu, D Xu, Y Zhou - Signal transduction and …, 2021 - nature.com
Abstract The Coronavirus Disease 2019 (COVID-19) pandemic has become a global crisis
and is more devastating than any other previous infectious disease. It has affected a …
and is more devastating than any other previous infectious disease. It has affected a …
Host-directed immunotherapy of viral and bacterial infections: past, present and future
The advent of COVID-19 and the persistent threat of infectious diseases such as
tuberculosis, malaria, influenza and HIV/AIDS remind us of the marked impact that infections …
tuberculosis, malaria, influenza and HIV/AIDS remind us of the marked impact that infections …
SARS-CoV-2-specific immune response and the pathogenesis of COVID-19
E Gusev, A Sarapultsev, L Solomatina… - International journal of …, 2022 - mdpi.com
The review aims to consolidate research findings on the molecular mechanisms and
virulence and pathogenicity characteristics of coronavirus disease (COVID-19) causative …
virulence and pathogenicity characteristics of coronavirus disease (COVID-19) causative …
[HTML][HTML] Characteristics of SARS-CoV-2 and COVID-19
B Hu, H Guo, P Zhou, ZL Shi - Nature reviews microbiology, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible
and pathogenic coronavirus that emerged in late 2019 and has caused a pandemic of acute …
and pathogenic coronavirus that emerged in late 2019 and has caused a pandemic of acute …
Immunity, endothelial injury and complement-induced coagulopathy in COVID-19
In December 2019, a novel coronavirus was isolated from the respiratory epithelium of
patients with unexplained pneumonia in Wuhan, China. This pathogen, named severe acute …
patients with unexplained pneumonia in Wuhan, China. This pathogen, named severe acute …
Evasion of type I interferon by SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication and host
immune response determine coronavirus disease 2019 (COVID-19), but studies evaluating …
immune response determine coronavirus disease 2019 (COVID-19), but studies evaluating …