Toll-like receptors activation, signaling, and targeting: an overview
SR El-Zayat, H Sibaii, FA Mannaa - Bulletin of the National Research …, 2019 - Springer
Abstract Background Toll-like receptors (TLRs) are an important family of receptors that
constitute the first line of defense system against microbes. They can recognize both …
constitute the first line of defense system against microbes. They can recognize both …
Oxidative stress in autism spectrum disorder—current progress of mechanisms and biomarkers
X Liu, J Lin, H Zhang, NU Khan, J Zhang… - Frontiers in …, 2022 - frontiersin.org
Autism spectrum disorder (ASD) is a type of neurodevelopmental disorder that has been
diagnosed in an increasing number of children around the world. Existing data suggest that …
diagnosed in an increasing number of children around the world. Existing data suggest that …
Beyond infection-Maternal immune activation by environmental factors, microglial development, and relevance for autism spectrum disorders
Immune molecules such as cytokines and chemokines and the cells that produce them
within the brain, notably microglia, are critical for normal brain development. This recognition …
within the brain, notably microglia, are critical for normal brain development. This recognition …
The use of biomarkers associated with leaky gut as a diagnostic tool for early intervention in autism spectrum disorder: a systematic review
Background Innovative research highlighted the probable connection between autism
spectrum disorder (ASD) and gut microbiota as many autistic individuals have …
spectrum disorder (ASD) and gut microbiota as many autistic individuals have …
Immune abnormalities in autism spectrum disorder—could they hold promise for causative treatment?
D Gładysz, A Krzywdzińska, KK Hozyasz - Molecular neurobiology, 2018 - Springer
Autism spectrum disorders (ASD) are characterized by impairments in language and
communication development, social behavior, and the occurrence of stereotypic patterns of …
communication development, social behavior, and the occurrence of stereotypic patterns of …
The impact of glutathione metabolism in autism spectrum disorder
This paper reviews the potential role of glutathione (GSH) in autism spectrum disorder
(ASD). GSH plays a key role in the detoxification of xenobiotics and maintenance of balance …
(ASD). GSH plays a key role in the detoxification of xenobiotics and maintenance of balance …
Differential regulation of Nrf2 is linked to elevated inflammation and nitrative stress in monocytes of children with autism
Autism spectrum disorder (ASD) is a very complex neurodevelopmental disorder
characterized by deficits in social and communication skills. Innate immune cells like …
characterized by deficits in social and communication skills. Innate immune cells like …
Imbalance in pro-inflammatory and anti-inflammatory cytokines milieu in B cells of children with autism
B cells play multiple roles in preservation of healthy immune system including management
of immune responses by expression of pro-and anti-inflammatory cytokines. Several earlier …
of immune responses by expression of pro-and anti-inflammatory cytokines. Several earlier …
Role of JAK-STAT and PPAR-gamma signalling modulators in the prevention of autism and neurological dysfunctions
The Janus-kinase (JAK) and signal transducer activator of transcription (STAT) signalling
pathways regulate gene expression and control various factors involved in normal …
pathways regulate gene expression and control various factors involved in normal …
Protective effects of vanillic acid on autistic-like behaviors in a rat model of maternal separation stress: Behavioral, electrophysiological, molecular and …
Compounds derived from herbs exhibit a range of biological properties, including anti-
inflammatory, antioxidant, and neuroprotective properties. However, the exact mechanism of …
inflammatory, antioxidant, and neuroprotective properties. However, the exact mechanism of …