The quality and developmental capacity of oocytes derived from in vitro maturation (IVM)
remain unsatisfactory, which greatly impairs the efficiency and application of embryo …

The regulation of early events in mammalian embryonic development is a complex process.
In the early stages, pluripotency, cellular differentiation, and growth should occur at specific …

Transforming growth factor-beta (TGF-β) plays a critical role in regulating trophoblast
invasion and proliferation. Growth differentiation factor-8 (GDF-8) is a member of the TGF-β …

Rationale: Aortic dissection (AD) is caused by functional disorder of cells in the aortic wall,
which is largely attributed to vascular remodeling. Therapeutic strategies for AD remain …

Pregnancy is a complex process in which significant changes occur continually in both the
corpora lutea and in the endometrium of the females and varies depending on the …

Objectives Gene regulation in early embryos has been widely studied for a long time
because lineage segregation gives rise to the formation of a pluripotent cell population …

Interleukin-7 (IL-7), a vital factor that affects cell development, proliferation, and survival,
plays an important role in oocyte maturation. However, its role in embryonic development …

Neurotrophin-4 (NT-4), a neurotrophic factor, appears to affect early embryonic development
because it is secreted not only by neurons but also by oviductal and uterine epithelial cells …

Objective Myo-inositol (Myo-Ins), the most abundant form of inositol, is an antioxidant and
plays a crucial role in the development and reproduction of mammals and humans …

In vitro fertilization (IVF) technology for embryo production has been applied in basic
research, animal husbandry and medicine. However, the developmental efficiency and …