Restoring synovial homeostasis in rheumatoid arthritis by targeting fibroblast-like synoviocytes
G Nygaard, GS Firestein - Nature Reviews Rheumatology, 2020 - nature.com
Rheumatoid arthritis (RA) is a chronic immune-mediated disease that primarily affects the
synovium of diarthrodial joints. During the course of RA, the synovium transforms into a …
synovium of diarthrodial joints. During the course of RA, the synovium transforms into a …
Molecular genetics and diagnosis of thyroid cancer
YE Nikiforov, MN Nikiforova - Nature Reviews Endocrinology, 2011 - nature.com
Thyroid cancer is a common type of endocrine malignancy, and its incidence has been
steadily increasing in many regions of the world. Initiation and progression of thyroid cancer …
steadily increasing in many regions of the world. Initiation and progression of thyroid cancer …
The American Association of Endocrine Surgeons guidelines for the definitive surgical management of thyroid disease in adults
KN Patel, L Yip, CC Lubitz, EG Grubbs, BS Miller… - Annals of …, 2020 - journals.lww.com
Objective: To develop evidence-based recommendations for safe, effective, and appropriate
thyroidectomy. Background: Surgical management of thyroid disease has evolved …
thyroidectomy. Background: Surgical management of thyroid disease has evolved …
A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine
DC Wallace - Annu. Rev. Genet., 2005 - annualreviews.org
Life is the interplay between structure and energy, yet the role of energy deficiency in human
disease has been poorly explored by modern medicine. Since the mitochondria use …
disease has been poorly explored by modern medicine. Since the mitochondria use …
Diagnostic terminology and morphologic criteria for cytologic diagnosis of thyroid lesions: a synopsis of the National Cancer Institute Thyroid Fine‐Needle Aspiration …
ZW Baloch, VA LiVolsi, SL Asa, J Rosai… - Diagnostic …, 2008 - Wiley Online Library
Abstract The National Cancer Institute (NCI) sponsored the NCI Thyroid Fine‐needle
Aspiration (FNA) State of the Science Conference on October 22–23, 2007 in Bethesda, MD …
Aspiration (FNA) State of the Science Conference on October 22–23, 2007 in Bethesda, MD …
Pathogenetic mechanisms in thyroid follicular-cell neoplasia
Thyroid cancer is one of the few malignancies that are increasing in incidence. Recent
advances have improved our understanding of its pathogenesis; these include the …
advances have improved our understanding of its pathogenesis; these include the …
Mitochondrial mutations in cancer
M Brandon, P Baldi, DC Wallace - Oncogene, 2006 - nature.com
The metabolism of solid tumors is associated with high lactate production while growing in
oxygen (aerobic glycolysis) suggesting that tumors may have defects in mitochondrial …
oxygen (aerobic glycolysis) suggesting that tumors may have defects in mitochondrial …
Defects in mitochondrial metabolism and cancer
Cancer is a heterogeneous set of diseases characterized by different molecular and cellular
features. Over the past decades, researchers have attempted to grasp the complexity of …
features. Over the past decades, researchers have attempted to grasp the complexity of …
Mitochondrial DNA mutations in human cancer
A Chatterjee, E Mambo, D Sidransky - Oncogene, 2006 - nature.com
Somatic mitochondrial DNA (mtDNA) mutations have been increasingly observed in primary
human cancers. As each cell contains many mitochondria with multiple copies of mtDNA, it …
human cancers. As each cell contains many mitochondria with multiple copies of mtDNA, it …
Mitochondrial defects in cancer
JS Carew, P Huang - Molecular cancer, 2002 - Springer
Mitochondria play important roles in cellular energy metabolism, free radical generation, and
apoptosis. Defects in mitochondrial function have long been suspected to contribute to the …
apoptosis. Defects in mitochondrial function have long been suspected to contribute to the …