Rational design of hyperstable antibacterial peptides for food preservation
We describe the design of peptides with properties like thermostability, pH stability, and
antibacterial activity against a few bacterial food pathogens. Insights obtained from classical …
antibacterial activity against a few bacterial food pathogens. Insights obtained from classical …
Binding mechanisms of amyloid-like peptides to lipid bilayers and effects of divalent cations
In several neurodegenerative diseases, cell toxicity can emerge from damage produced by
amyloid aggregates to lipid membranes. The details accounting for this damage are poorly …
amyloid aggregates to lipid membranes. The details accounting for this damage are poorly …
Peptide–Membrane Binding: Effects of the Amino Acid Sequence
An understanding of how the amino acid sequence affects the interaction of peptides with
lipid membranes remains mostly unknown. This type of knowledge is required to rationalize …
lipid membranes remains mostly unknown. This type of knowledge is required to rationalize …
Deciphering the Mechanism of Action of the Antimicrobial Peptide BP100
G Riesco-Llach, S Llanet-Ferrer, M Planas… - International Journal of …, 2024 - mdpi.com
The linear undecapeptide KKLFKKILKYL-NH2 (BP100) highlights for its antibacterial activity
against Gram-negative bacteria and its low toxicity. These excellent biological properties …
against Gram-negative bacteria and its low toxicity. These excellent biological properties …
Membrane Penetrating-Cationic Peptide BP100 Functionalized Silver Nanoparticles as Efficient Antibacterial Agents
N Devi, Saima, SK Pandey, D Kaur… - ACS Applied Nano …, 2024 - ACS Publications
In the present scenario, resistance to antibiotics has become a threatening situation for
public health. To find a solution for this, conjugation of a cationic peptide with silver …
public health. To find a solution for this, conjugation of a cationic peptide with silver …
Polymer-coated gold nanoparticles and polymeric nanoparticles as nanocarrier of the BP100 antimicrobial peptide through a lung surfactant model
Pneumonia is caused by microorganisms that settle in the lungs, which may reach the
pulmonary alveoli and cause respiratory failure. Antibiotic treatments are the most used …
pulmonary alveoli and cause respiratory failure. Antibiotic treatments are the most used …
How insertion of a single tryptophan in the N-terminus of a cecropin A-melittin hybrid peptide changes its antimicrobial and biophysical profile
In the era of antibiotic resistance, there is an urgent need for efficient antibiotic therapies to
fight bacterial infections. Cationic antimicrobial peptides (CAMP) are promising lead …
fight bacterial infections. Cationic antimicrobial peptides (CAMP) are promising lead …
Atomic insights into amyloid-induced membrane damage
Amphipathic peptides can cause biological membranes to leak either by dissolving their
lipid content via a detergent-like mechanism or by forming pores on the membrane surface …
lipid content via a detergent-like mechanism or by forming pores on the membrane surface …
Theoretical investigation of solvent and oxidation/deprotonation effects on the electronic structure of a mononuclear Ru-aqua-polypyridine complex in aqueous …
Mononuclear polypyridine ruthenium (Ru) complexes can catalyze various reactions,
including water splitting, and can also serve as photosensitizers in solar cells. Despite …
including water splitting, and can also serve as photosensitizers in solar cells. Despite …
Vesicle protrusion induced by antimicrobial peptides suggests common carpet mechanism for short antimicrobial peptides
Short-cationic alpha-helical antimicrobial peptides (SCHAMPs) are promising candidates to
combat the growing global threat of antimicrobial resistance. They are short-sequenced …
combat the growing global threat of antimicrobial resistance. They are short-sequenced …