Membrane fusion is a universal feature of eukaryotic protein trafficking and is mediated by
the soluble N-ethylmaleimide sensitive factor attachment protein receptor (SNARE) family …

Wnt signaling plays critical roles during synaptic development and plasticity. However, the
mechanisms by which Wnts are released and travel to target cells are unresolved. During …

Soluble N‐ethylmaleimide‐sensitive factor attachment protein receptors (SNAREs) are
universal molecular engines that drive membrane fusion. Particularly, synaptic SNAREs …

Neurexins are key adhesion proteins that coordinate extracellular and intracellular synaptic
components. Nonetheless, the low abundance of these multidomain proteins has …

Synaptic plasticity is a fundamental feature of the nervous system that allows adaptation to
changing behavioral environments. Most studies of synaptic plasticity have examined the …

Tissue–tissue communications are integral to organismal aging, orchestrating a body-wide
aging process. The brain plays a key role in this process by detecting and processing …

Synaptic-s oluble N-ethylmaleimide-sensitive factor a ttachment re ceptor (SNARE) proteins
couple their stage-wise folding/assembly to rapid exocytosis of neurotransmitters in a …

The synaptic vesicle protein synaptobrevin engages with syntaxin and SNAP-25 to form the
SNARE complex, which drives membrane fusion in neuronal exocytosis. In the SNARE …

Sleep is a dynamic process in most animals, involving distinct stages that probably perform
multiple functions for the brain. Before sleep functions can be initiated, it is likely that …

Abstract Bone Morphogenetic Protein (BMP) signaling is essential for craniofacial
development, though little is known about the mechanisms that govern BMP secretion. We …