Biomarkers for prostate cancer: prostate-specific antigen and beyond

MJ Duffy - Clinical Chemistry and Laboratory Medicine (CCLM), 2020 - degruyter.com
In recent years, several new biomarkers supplementing the role of prostate-specific antigen
(PSA) have become available for men with prostate cancer. Although widely used in an ad …

EAU-ESTRO-SIOG guidelines on prostate cancer. Part 1: screening, diagnosis, and local treatment with curative intent

N Mottet, J Bellmunt, M Bolla, E Briers… - European urology, 2017 - Elsevier
Objective To present a summary of the 2016 version of the European Association of Urology
(EAU)-European Society for Radiotherapy & Oncology (ESTRO)-International Society of …

All change in the prostate cancer diagnostic pathway

DJ Lomas, HU Ahmed - Nature reviews Clinical oncology, 2020 - nature.com
Following detection of high levels of serum prostate-specific antigen, many men are advised
to have transrectal ultrasound-guided biopsy in an attempt to locate a cancer. This …

Assessing the clinical impact of risk prediction models with decision curves: guidance for correct interpretation and appropriate use

KF Kerr, MD Brown, K Zhu, H Janes - Journal of Clinical Oncology, 2016 - ascopubs.org
The decision curve is a graphical summary recently proposed for assessing the potential
clinical impact of risk prediction biomarkers or risk models for recommending treatment or …

Prostate cancer screening in men aged 50–69 years (STHLM3): a prospective population-based diagnostic study

H Grönberg, J Adolfsson, M Aly, T Nordström… - The lancet …, 2015 - thelancet.com
Background The prostate-specific antigen (PSA) test is used to screen for prostate cancer
but has a high false-positive rate that translates into unnecessary prostate biopsies and …

NCCN guidelines insights: prostate cancer early detection, version 2.2016

PR Carroll, JK Parsons, G Andriole… - Journal of the National …, 2016 - jnccn.org
The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Prostate Cancer
Early Detection provide recommendations for prostate cancer screening in healthy men who …

Prostate-specific antigen (PSA) density in the diagnostic algorithm of prostate cancer

T Nordström, O Akre, M Aly, H Grönberg… - Prostate cancer and …, 2018 - nature.com
Background Screening for prostate cancer using prostate-specific antigen (PSA) alone leads
to un-necessary biopsying and overdiagnosis. PSA density is easily accessible, but early …

Prostate cancer screening

WJ Catalona - Medical Clinics, 2018 - medical.theclinics.com
The US Preventive Services Task Force (USPSTF) has dropped its opposition to routine
prostate cancer (PCa) screening in favor of a shared decision-making process between men …

Prostate cancer screening using a combination of risk-prediction, MRI, and targeted prostate biopsies (STHLM3-MRI): a prospective, population-based, randomised …

T Nordström, A Discacciati, M Bergman… - The Lancet …, 2021 - thelancet.com
Background Screening for prostate cancer using prostate-specific antigen (PSA) reduces
prostate cancer mortality but can lead to adverse outcomes. We aimed to compare a …

[HTML][HTML] Diagnostic accuracy of liquid biomarkers for clinically significant prostate cancer detection: a systematic review and diagnostic meta-analysis of multiple …

T Kawada, SR Shim, F Quhal, P Rajwa… - European urology …, 2024 - Elsevier
Context Many liquid biomarkers have entered clinical practice with the praise to improve the
detection of clinically significant prostate cancer (csPCa), hel** avoid unnecessary …