Resolution of inflammation: An organizing principle in biology and medicine

D Panigrahy, MM Gilligan, CN Serhan… - Pharmacology & …, 2021 - Elsevier
The resolution of inflammation has emerged as a critical endogenous process that protects
host tissues from prolonged or excessive inflammation that can become chronic. Failure of …

Resolvins in inflammation: emergence of the pro-resolving superfamily of mediators

CN Serhan, BD Levy - The Journal of clinical investigation, 2018 - Am Soc Clin Investig
Countless times each day, the acute inflammatory response protects us from invading
microbes, injuries, and insults from within, as in surgery-induced tissue injury. These …

[图书][B] Newman and Carranza's Clinical Periodontology: Newman and Carranza's Clinical Periodontology E-Book

MG Newman, H Takei, PR Klokkevold, FA Carranza - 2018 - books.google.com
From basic science and fundamental procedures to the latest advanced techniques in
reconstructive, esthetic, and implant therapy, Newman and Carranza's Clinical …

Carcinogenesis: Failure of resolution of inflammation?

A Fishbein, BD Hammock, CN Serhan… - Pharmacology & …, 2021 - Elsevier
Inflammation in the tumor microenvironment is a hallmark of cancer and is recognized as a
key characteristic of carcinogens. However, the failure of resolution of inflammation in …

Pro-resolving lipid mediators are leads for resolution physiology

CN Serhan - Nature, 2014 - nature.com
Advances in our understanding of the mechanisms that bring about the resolution of acute
inflammation have uncovered a new genus of pro-resolving lipid mediators that include the …

The resolution code of acute inflammation: Novel pro-resolving lipid mediators in resolution

CN Serhan, N Chiang, J Dalli - Seminars in immunology, 2015 - Elsevier
Studies into the mechanisms in resolution of self-limited inflammation and acute reperfusion
injury have uncovered a new genus of pro-resolving lipid mediators coined specialized pro …

Proresolving lipid mediators and mechanisms in the resolution of acute inflammation

CD Buckley, DW Gilroy, CN Serhan - Immunity, 2014 - cell.com
Inflammatory responses, like all biological cascades, are shaped by a delicate balance
between positive and negative feedback loops. It is now clear that in addition to positive and …

Lipid mediators in the resolution of inflammation

CN Serhan, N Chiang, J Dalli… - Cold Spring Harbor …, 2015 - cshperspectives.cshlp.org
Mounting of the acute inflammatory response is crucial for host defense and pivotal to the
development of chronic inflammation, fibrosis, or abscess formation versus the protective …

Resolvins and protectins in inflammation resolution

CN Serhan, NA Petasis - Chemical reviews, 2011 - ACS Publications
The critical role of inflammatory processes in health and disease has long been recognized,
1 yet the detailed molecular mechanisms and biological events that regulate the progression …

New pro-resolving n-3 mediators bridge resolution of infectious inflammation to tissue regeneration

CN Serhan, N Chiang, J Dalli - Molecular aspects of medicine, 2018 - Elsevier
While protective, the acute inflammatory response when uncontrolled can lead to further
tissue damage and chronic inflammation that is now widely recognized to play important …