Potential and therapeutic roles of diosmin in human diseases

E Huwait, M Mobashir - Biomedicines, 2022 - mdpi.com
Because of their medicinal characteristics, effectiveness, and importance, plant-derived
flavonoids have been a possible subject of research for many years, particularly in the last …

Deciphering molecular landscape of breast cancer progression and insights from functional genomics and therapeutic explorations followed by in vitro validation

B Khan, R Qahwaji, MS Alfaifi, T Athar, A Khan… - Scientific Reports, 2024 - nature.com
Breast cancer is caused by aberrant breast cells that proliferate and develop into tumors.
Tumors have the potential to spread throughout the body and become lethal if ignored …

Synthesis of silver nano particles using myricetin and the in-vitro assessment of anti-colorectal cancer activity: In-silico integration

ST Anwer, M Mobashir, OI Fantoukh, B Khan… - International Journal of …, 2022 - mdpi.com
The creation of novel anticancer treatments for a variety of human illnesses, including
different malignancies and dangerous microbes, also potentially depends on nanoparticles …

Understanding the role of potential pathways and its components including hypoxia and immune system in case of oral cancer

LH Bajrai, SS Sohrab, M Mobashir, MA Kamal… - Scientific Reports, 2021 - nature.com
There are a few biological functions or phenomenon which are universally associated with
majority of the cancers and hypoxia and immune systems are among them. Hypoxia often …

[PDF][PDF] Therapeutic agents for the management of atherosclerosis from herbal sources: A computational approach

EA Huwait - Jour. Bas. Sci, 2024 - jbsciences.com
One of the most prevalent illnesses in the world, atherosclerosis has a significant role in the
development of hypertension, stroke, myocardial localised necrosis, and several other …

An approach for systems-level understanding of prostate cancer from high-throughput data integration to pathway modeling and simulation

M Mobashir, SP Turunen, MA Izhari, IM Ashankyty… - Cells, 2022 - mdpi.com
To understand complex diseases, high-throughput data are generated at large and multiple
levels. However, extracting meaningful information from large datasets for comprehensive …

A network-guided approach to discover phytochemical-based anticancer therapy: Targeting MARK4 for hepatocellular carcinoma

S Ahmed, M Mobashir, LA Al-Keridis… - Frontiers in …, 2022 - frontiersin.org
MAP/microtubule affinity-regulating kinase 4 (MARK4) is associated with various biological
functions, including neuronal migration, cell polarity, microtubule dynamics, apoptosis, and …

Genomic profiling and network-level understanding uncover the potential genes and the pathways in hepatocellular carcinoma

SA El-Kafrawy, MM El-Daly, LH Bajrai… - Frontiers in …, 2022 - frontiersin.org
Data integration with phenotypes such as gene expression, pathways or function, and
protein-protein interactions data has proven to be a highly promising technique for …

Gene Expression Profiling of Early Acute Febrile Stage of Dengue Infection and Its Comparative Analysis With Streptococcus pneumoniae Infection

LH Bajrai, SS Sohrab, TA Alandijany… - Frontiers in Cellular …, 2021 - frontiersin.org
Infectious diseases are the disorders caused by organisms such as bacteria, viruses, fungi,
or parasites. Although many of them are permentantly hazardous, a number of them live in …

Effects of Autophagy‐Related Genes on the Prognosis and Immune Microenvironment of Ovarian Cancer

J Zhang, H Yan, Y Fu - BioMed Research International, 2022 - Wiley Online Library
Ovarian cancer (OC) is among the most malignant tumors of the female reproductive system.
The role of autophagy in cancer is complex, and the functional relationship between …