Graphene quantum dots as a potential diagnostic and therapeutic tool for the management of Alzheimer's disease

S Ghosh, B Sachdeva, P Sachdeva, V Chaudhary… - Carbon Letters, 2022 - Springer
Alzheimer's disease (AD) is one of the most common forms of dementia, affecting more than
50 million people globally. The onset of AD is linked to age, smoking, obesity …

Benefits and limitations of nanomedicine treatment of brain cancers and age-dependent neurodegenerative disorders

ME Neganova, YR Aleksandrova… - Seminars in Cancer …, 2022 - Elsevier
The treatment of central nervous system (CNS) malignancies, including brain cancers, is
limited by a number of obstructions, including the blood-brain barrier (BBB), the …

Intranasal oxytocin attenuates cognitive impairment, β-amyloid burden and tau deposition in female rats with Alzheimer's disease: interplay of ERK1/2/GSK3β/caspase …

SO El-Ganainy, OA Soliman, AA Ghazy, M Allam… - Neurochemical …, 2022 - Springer
Oxytocin is a neuropeptide hormone that plays an important role in social bonding and
behavior. Recent studies indicate that oxytocin could be involved in the regulation of …

[HTML][HTML] Photobiomodulation in Alzheimer's disease—A complementary method to state-of-the-art pharmaceutical formulations and nanomedicine?

LM Ailioaie, C Ailioaie, G Litscher - Pharmaceutics, 2023 - mdpi.com
Alzheimer's disease (AD), as a neurodegenerative disorder, usually develops slowly but
gradually worsens. It accounts for approximately 70% of dementia cases worldwide, and is …

A review of chitosan-based nanocarriers as drug delivery systems for brain diseases: Critical challenges, outlooks and promises

K Khodaverdi, A Bakhshi, MR Mozafari… - International Journal of …, 2024 - Elsevier
The administration of medicinal drugs orally or systemically limits the treatment of specific
central nervous system (CNS) illnesses, such as certain types of brain cancers. These …

Engineering of structural and functional properties of nanotherapeutics and nanodiagnostics for intranasal brain targeting in Alzheimer's

NS Hinge, H Kathuria, MM Pandey - Applied Materials Today, 2022 - Elsevier
Alzheimer's disease (AD) is the fifth leading cause of death on the planet. It hallmarks the
presence of amyloid plaques and neurofibrillary tangles in geriatric patients. The condition …

“Plurol will not miss the boat”: A new manifesto of galantamine conveyance

HA Gad, M Mansour, H Abbas, RT Malatani… - Journal of Drug Delivery …, 2022 - Elsevier
Liquid crystalline nanoparticles (LCNPs) are lipid self-assembled nanostructures that meet
plenty of advantageous features. The commonly used substrates for LCNPs preparation are …

Oxymatrine-mediated prevention of amyloid β-peptide-induced apoptosis on Alzheimer's model PC12 cells: in vitro cell culture studies and in vivo cognitive …

Y Zhu, Z Wang, C Gao, L Zhang, R Sui - Inflammopharmacology, 2023 - Springer
Alzheimer's disease (AD) is a major neurological disease affecting elderly individuals
worldwide. Existing drugs only reduce the symptoms of the disease without addressing the …

Nanoparticle formulations for the improvement of symptomatic treatments of neurodegenerative disorders

I Boyton, C Rennie, LE Collins‐Praino… - ChemNanoMat, 2024 - Wiley Online Library
Neuronanomedicine merges nanotechnology and neuroscience in the pursuit of
engineering therapeutic interventions for neurological disorders, including Alzheimer's …

Intranasal delivery of chitosan-based nanoparticles as an innovative way for management of neurodegenerative disorders: A comprehensive review of advanced …

RM Ibrahim, M Teaima, M El-Nabarawi… - Journal of Drug Delivery …, 2024 - Elsevier
Neurodegenerative disorders are chronic conditions related to brain malfunctions. The
presence of the blood-brain barrier creates obstacles to the management of central nervous …