[HTML][HTML] Molecular docking, drug-likeness and DFT study of some modified tetrahydrocurcumins as potential anticancer agents

A Mahal, M Al-Janabi, V Eyüpoğlu, A Alkhouri… - Saudi Pharmaceutical …, 2024 - Elsevier
The present study utilized molecular docking and density functional theory (DFT)
approaches, and ADMET (absorption, distribution, metabolism, excretion, and toxicity) …

[HTML][HTML] Pd-, Cu-, and Ni-Catalyzed Reactions: A Comprehensive Review of the Efficient Approaches towards the Synthesis of Antibacterial Molecules

A Zia, S Khalid, N Rasool, N Mohsin, M Imran, SI Toma… - Pharmaceuticals, 2024 - mdpi.com
A strong synthetic tool for many naturally occurring chemicals, polymers, and
pharmaceutical substances is transition metal-catalyzed synthesis. A serious concern to …

Green synthesis and antimicrobial activity of copper nanoparticles (Cu-NPS) by Piper longum fruit extract

A Mahal, E Mahal, S Al-Mutlaq, AH Daham… - Bulletin of the Chemical …, 2024 - ajol.info
Many applications of green synthesis in the field of environment and biomedicine aiming at
decreasing the use of toxic chemicals through utilizing of plants which are safe. In this study …

Synthesis, molecular docking studies of formononetin derivatives as potent Bax agonists for anticancer activity

WD Jia, X Bai, QQ Ma, M Bian, CM Bai, D Li… - Natural Product …, 2025 - Taylor & Francis
Formononetin as a Bax agonist exhibits anticancer effects. To identify novel Bax agonist, 18
new structurally modified formononetin derivatives were synthesised and their anticancer …

Synthesis of novel quinolines with antibacterial activity

DS Zinad, A Mahal, GA Salman… - Organic Preparations …, 2024 - Taylor & Francis
In recent years, the development of pharmaceuticals and high-value fine chemicals based
on heterocycles has sustained strong activity. 1-12 Discovery of new medicines based on …

Design, synthesis and antibacterial evaluation of a novel class of tetrahydrobenzothiophene derivatives

L Lai, J Yang, W Sun, X Su, J Chen, X Chen… - RSC Medicinal …, 2023 - pubs.rsc.org
In this study, a new series of tetrahydrobenzothiophene derivatives have been designed.
Newly designed molecules have been synthesized through a medicinal chemistry route, and …

One‐Pot Synthesis of 3‐Amino‐1, 2, 4‐triazoles Using Choline Chloride‐Urea and Their Antibacterial Activities

M Arab, H Beyzaei, R Aryan - ChemistrySelect, 2022 - Wiley Online Library
In this study, a new one‐pot method was proposed for the synthesis of novel and known 3‐
amino‐1, 2, 4‐triazole derivatives in choline chloride/urea (1: 2) as a biodegradable …

Synthesis of substituted 2-amino oxazoles with their cobalt (II) and platinum (IV) complexes and evaluation of their biological activity

AZ Husain, YS Al-Jawaheri, AY Al-Assafe - Bulletin of the Chemical Society …, 2024 - ajol.info
Many applications of green synthesis in the field of environment and biomedicine aiming at
decreasing the use of toxic chemicals through utilizing of plants which are safe. In this study …

A Green Synthesis of Nitrogen Containing Novel Tetraazaaceanthrylene Derivatives Under Catalyst‐free Conditions: Docking studies, ADME and Antibacterial Activity

G Sankar, N Vinoth, N Nagasundaram… - …, 2022 - Wiley Online Library
A facile and convenient greener route has been introduced for the synthesis of novel 2‐
phenyl‐2, 3, 5, 6‐tetraazaaceanthrylene‐1, 4 (2H, 5H)‐dione derivatives via one pot three …

[PDF][PDF] Antibacterial activity of Cassia angustifolia. Vahl (Sinameki) leaf extract against some pathogenic bacteria

FH Kamela, CN Fathullab, A Mahalc, A Alkhouric… - researchgate.net
Antimicrobials are likely one of the most effective kinds of chemotherapy in medical history
and used to prevent and treat infections caused by bacteria. Antibiotics play an important …