Pathogenesis and current treatment strategies of hepatocellular carcinoma

D Tümen, P Heumann, K Gülow, CN Demirci… - Biomedicines, 2022 - mdpi.com
Hepatocellular carcinoma (HCC) is the most frequent liver cancer with high lethality and low
five-year survival rates leading to a substantial worldwide burden for healthcare systems …

MicroRNAs in extracellular vesicles: Sorting mechanisms, diagnostic value, isolation, and detection technology

D Xu, K Di, B Fan, J Wu, X Gu, Y Sun… - … in bioengineering and …, 2022 - frontiersin.org
MicroRNAs (miRNAs) are a class of short, single-stranded, noncoding RNAs, with a length
of about 18–22 nucleotides. Extracellular vesicles (EVs) are derived from cells and play a …

microRNA‐based diagnostic and therapeutic applications in cancer medicine

LF Sempere, AS Azmi, A Moore - Wiley Interdisciplinary …, 2021 - Wiley Online Library
It has been almost two decades since the first link between microRNAs and cancer was
established. In the ensuing years, this abundant class of short noncoding regulatory RNAs …

Analysis and biomedical applications of functional cargo in extracellular vesicles

F Qian, Z Huang, H Zhong, Q Lei, Y Ai, Z **e, T Zhang… - ACS …, 2022 - ACS Publications
Extracellular vesicles (EVs) can facilitate essential communication among cells in a range of
pathophysiological conditions including cancer metastasis and progression, immune …

The key role of exosomes on the pre-metastatic niche formation in tumors

X Yang, Y Zhang, Y Zhang, S Zhang, L Qiu… - Frontiers in molecular …, 2021 - frontiersin.org
Exosomes or other extracellular vesicles released from cells play an important role in cell-to-
cell communication by transferring bio-information (DNA, coding/non-coding RNA, and …

From conventional to microfluidic: progress in extracellular vesicle separation and individual characterization

M Chen, S Lin, C Zhou, D Cui, H Haick… - Advanced Healthcare …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) are nanoscale membrane vesicles, which contain a wide variety
of cargo such as proteins, miRNAs, and lipids. A growing body of evidence suggests that …

[HTML][HTML] A comprehensive review of the potential role of liquid biopsy as a diagnostic, prognostic, and predictive biomarker in pancreatic ductal adenocarcinoma

K Stosic, OA Senar, J Tarfouss, C Bouchart, J Navez… - Cells, 2023 - mdpi.com
Pancreatic ductal adenocarcinoma is one of the most lethal malignant diseases, with a
mortality rate being close to incidence. Due to its heterogeneity and plasticity, as well as the …

Updates on clinical use of liquid biopsy in colorectal cancer screening, diagnosis, follow-up, and treatment guidance

O Mazouji, A Ouhajjou, R Incitti… - Frontiers in Cell and …, 2021 - frontiersin.org
Colorectal cancer (CRC) is one of the most common cancers worldwide, being the third most
diagnosed in the world and the second deadliest. Solid biopsy provides an essential guide …

Liquid biopsy in pancreatic cancer: are we ready to apply it in the clinical practice?

V Heredia-Soto, N Rodríguez-Salas, J Feliu - Cancers, 2021 - mdpi.com
Simple Summary Pancreatic ductal adenocarcinoma (PDAC) is one of the tumors with the
highest mortality, for which survival has hardly changed in the last 40 years. This high …

Nanomaterials for miRNA detection: the hybridization chain reaction strategy

B Mohan, S Kumar, S Kumar, K Modi, D Tyagi… - Sensors & …, 2023 - pubs.rsc.org
MicroRNAs (miRNAs) with nucleotides are a class of endogenous small RNAs and can play
crucial functions in diagnosing diseases. In particular, the group of miRNAs is responsible …