Approaches to improve the taste of oral dosage forms that contain unpleasant tasting drugs
are versatile. Likewise, the analytical in vitro and in vivo methods to assess taste-masking …

Conventional adult dosage forms are often not suitable for the paediatric and geriatric
populations due to either swallowing difficulties or patient repulsion and a requirement for …

We propose a generalization of the Weibull dissolution model, referred to as generalized
Weibull dissolution model, that seamlessly captures all three fractional dissolution rates …

Solid dosage forms require the addition of different types of excipients such as flowability,
compressibility, disintegration, solubility, stability and other physical and chemical properties …

The majority of active pharmaceutical ingredients (APIs) found in oral dosage forms have a
bitter taste. Masking the unpleasant taste of bitter, APIs is a major challenge in the …

The purpose of the current study was to mask the taste of cetirizine HCl and to incorporate
the granules produced in oral disintegrating tablets (ODT). The bitter, active substance was …

Theophylline-loaded microparticles of a lipid carrier, Precirol® ATO 5, were prepared by the
ultrasonic spray-congealing method. The goal of the work was to investigate the effect of …

Nanoparticle preparation by the emulsification-solvent evaporation method is a complex
phenomenon. Various formulation factors can affect the internal structure and release of …

Undesirable taste is an important problem for patient compliance. Several oral
pharmaceuticals and bulking agents have disagreeable and bitter-tasting components. The …

The purpose of this research was to develop the taste-masked microspheres of intensely
bitter drug ondansetron hydrochloride (OSH) by spray-drying technique. The bitter taste …