Diagnosis of Parkinson's disease (PD) is commonly based on medical observations and
assessment of clinical signs, including the characterization of a variety of motor symptoms …

With the inexorable aging of the global populace, neurodegenerative diseases (NDs) like
Alzheimer's disease (AD), Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS) …

The differential diagnosis of parkinsonian syndromes is considered one of the most
challenging in neurology and error rates in the clinical diagnosis can be high even at …

Biomarkers in whichever modality are tremendously important in diagnosing of disease,
tracking disease progression and clinical trials. This applies in particular for disorders with a …

Background Cognitive impairment is a common non-motor symptom in Parkinson's disease.
So far, the underlying pathophysiology remains unclear. Several alterations in functional …

Parkinson's disease (PD) is a common, progressive, and currently incurable
neurodegenerative movement disorder. The diagnosis of PD is challenging, especially in …

Parkinson's disease (PD) is a neurodegenerative disorder that primarily affects the elderly
for over 55 years. PD can be characterised by patients exhibiting various non-motor and …

ABSTRACT Background Functional MRI (fMRI) has been widely used to study abnormal
patterns of functional connectivity at rest in patients with movement disorders such as …

Since anatomic MRI is presently not able to directly discern neuronal loss in Parkinson's
Disease (PD), studying the associated functional connectivity (FC) changes seems a …

Background Movement disorders such as Parkinson's disease are associated with structural
and functional changes in specific brain regions. Advanced magnetic resonance imaging …