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Multiplexed imaging in oncology
In oncology, technologies for clinical molecular imaging are used to diagnose patients,
establish the efficacy of treatments and monitor the recurrence of disease. Multiplexed …
establish the efficacy of treatments and monitor the recurrence of disease. Multiplexed …
Biological imaging of chemical bonds by stimulated Raman scattering microscopy
All molecules consist of chemical bonds, and much can be learned from map** the
spatiotemporal dynamics of these bonds. Since its invention a decade ago, stimulated …
spatiotemporal dynamics of these bonds. Since its invention a decade ago, stimulated …
Microglial lipid droplet accumulation in tauopathy brain is regulated by neuronal AMPK
The accumulation of lipid droplets (LDs) in aging and Alzheimer's disease brains is
considered a pathological phenomenon with unresolved cellular and molecular …
considered a pathological phenomenon with unresolved cellular and molecular …
Virtual histological staining of unlabelled tissue-autofluorescence images via deep learning
The histological analysis of tissue samples, widely used for disease diagnosis, involves
lengthy and laborious tissue preparation. Here, we show that a convolutional neural network …
lengthy and laborious tissue preparation. Here, we show that a convolutional neural network …
Super-resolution SRS microscopy with A-PoD
Stimulated Raman scattering (SRS) offers the ability to image metabolic dynamics with high
signal-to-noise ratio. However, its spatial resolution is limited by the numerical aperture of …
signal-to-noise ratio. However, its spatial resolution is limited by the numerical aperture of …
Vibrational spectroscopic imaging of living systems: An emerging platform for biology and medicine
BACKGROUND Biomolecules can serve as natural labels for microscopy by measuring their
molecular vibration spectra in living cells and tissues. However, the transition from …
molecular vibration spectra in living cells and tissues. However, the transition from …
Instant diagnosis of gastroscopic biopsy via deep-learned single-shot femtosecond stimulated Raman histology
Gastroscopic biopsy provides the only effective method for gastric cancer diagnosis, but the
gold standard histopathology is time-consuming and incompatible with gastroscopy …
gold standard histopathology is time-consuming and incompatible with gastroscopy …
Raman spectroscopy: techniques and applications in the life sciences
Raman spectroscopy is an increasingly popular technique in many areas, including biology
and medicine. It is based on Raman scattering, a phenomenon in which incident photons …
and medicine. It is based on Raman scattering, a phenomenon in which incident photons …
High-resolution, high-contrast mid-infrared imaging of fresh biological samples with ultraviolet-localized photoacoustic microscopy
Mid-infrared (MIR) microscopy provides rich chemical and structural information about
biological samples, without staining. Conventionally, the long MIR wavelength severely …
biological samples, without staining. Conventionally, the long MIR wavelength severely …
Raman spectroscopy and imaging in bioanalytics
D Cialla-May, C Krafft, P Rösch… - Analytical …, 2021 - ACS Publications
Since the discovery of the inelastic scattering of light, ie, the so-called Raman effect, 1
Raman spectroscopy has become an attractive tool in a high number of research fields …
Raman spectroscopy has become an attractive tool in a high number of research fields …