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[HTML][HTML] The METTL3-m6A Epitranscriptome: Dynamic Regulator of Epithelial Development, Differentiation, and Cancer
A Maldonado López, BC Capell - Genes, 2021 - mdpi.com
Dynamic modifications on RNA, frequently termed both,“RNA epigenetics” and
“epitranscriptomics”, offer one of the most exciting emerging areas of gene regulation and …
“epitranscriptomics”, offer one of the most exciting emerging areas of gene regulation and …
N6-methyladenosine RNA modification in head and neck squamous cell carcinoma (HNSCC): current status and future insights
P Janakiraman, JP Jayaprakash, SV Muralidharan… - Medical Oncology, 2024 - Springer
Abstract N6-methyladenosine (m6A) plays a pivotal role in regulating epitranscriptomic
mechanisms and is closely linked to the normal functioning of diverse classes of RNAs, both …
mechanisms and is closely linked to the normal functioning of diverse classes of RNAs, both …
KIAA1429/VIRMA promotes breast cancer progression by m6A‐dependent cytosolic HAS2 stabilization
Abstract N6‐methyladenosine (m6A), the most abundant internal modification in eukaryotic
mRNA, plays important roles in many physiological and pathological processes, including …
mRNA, plays important roles in many physiological and pathological processes, including …
DYNC1I1 acts as a promising prognostic biomarker and is correlated with immune infiltration in head and neck squamous cell carcinoma
RG Ananya, C Pandi, B Kannan, A Pandi… - Journal of Stomatology …, 2024 - Elsevier
Abstract Background/purpose Dynein Cytoplasmic 1 Intermediate Chain 1 (DYNC1I1) is a
crucial cytoplasmic dynein binding component, its high expression levels are associated …
crucial cytoplasmic dynein binding component, its high expression levels are associated …
METTL3-regulated m6A modification impairs the decidualization of endometrial stromal cells by regulating YTHDF2-mediated degradation of FOXO1 mRNA in …
X Li, J **, X Long, R Weng, W **ong, J Liang… - Reproductive Biology …, 2023 - Springer
Background Endometriosis-related infertility is a common worldwide reproductive health
concern. Despite ongoing research, the causes of infertility remain unclear. Evidence …
concern. Despite ongoing research, the causes of infertility remain unclear. Evidence …
METTL3 inhibitor STM2457 impairs tumor progression and enhances sensitivity to anlotinib in OSCC
L Liu, T Zhao, S Zheng, D Tang, H Han, C Yang… - Oral …, 2024 - Wiley Online Library
Objectives To investigate the inhibitory effects of STM2457, which is a novel METTL3 (m6A
writer) inhibitor, both as a monotherapy and in combination with anlotinib, in the treatment of …
writer) inhibitor, both as a monotherapy and in combination with anlotinib, in the treatment of …
Prognostic and clinicopathological significance of MRC2 expression in head and neck squamous cell carcinoma
K vinayakam Gopalakrishnan, B Kannan… - Journal of Stomatology …, 2023 - Elsevier
Background Head and neck squamous cell carcinoma (HNSCC) is one of the most
aggressive types of cancers worldwide, with metastasis being the major cause of death …
aggressive types of cancers worldwide, with metastasis being the major cause of death …
Extraction, characterization, and anticancer potential of extracellular polymeric substances from marine actinobacteria of Streptomyces species
ZM Noufal, P Sivaperumal… - Journal of advanced …, 2022 - journals.lww.com
To check the ability of the anticancer activity, the extracted extracellular polymeric
substances (EPS) from marine actinobacteria were done. Potential of the anticancer activity …
substances (EPS) from marine actinobacteria were done. Potential of the anticancer activity …
Oral squamous cell carcinoma gene patterns connected with RNA methylation for prognostic prediction
X Wu, J Tang, B Cheng - Oral Diseases, 2024 - Wiley Online Library
Objectives To determine whether m6A/m1A/m5C/m7G/m6Am/Ψ‐related genes influence the
prognosis of a patient with oral squamous cell carcinoma. Materials and Methods We …
prognosis of a patient with oral squamous cell carcinoma. Materials and Methods We …
Knowledge and awareness on various treatment modalities of diabetes mellitus-a observational survey
R Prasath, P Sinduja - 2023 - digibug.ugr.es
Introduction: Diabetes mellitus (DM) is a group of metabolic disorders characterized by a
high blood sugar level over a prolonged period of time. Patients suffer from various …
high blood sugar level over a prolonged period of time. Patients suffer from various …