Spontaneous electrical activity is a common feature of sensory systems during early
development. This sensory-independent neuronal activity has been implicated in promoting …

It has been hypothesized that tinnitus percepts may arise, in part, from increases in
spontaneous neural activity in the central auditory system. The DCN is the lowest central …

Loudness recruitment, an abnormally rapid growth of perceived loudness with sound level,
is a common symptom of sensorineural hearing loss. Following acoustic trauma, auditory …

There is an orderly topographic arrangement of neurones within auditory brainstem nuclei
based on sound frequency. Previous immunolabelling studies in the medial nucleus of the …

The excitability of CNS presynaptic terminals after a tetanic burst of action potentials is
important for synaptic plasticity. The mechanisms that regulate excitability, however, are not …

In neurons of the medial superior olive (MSO), voltage-gated ion channels control the
submillisecond time resolution of binaural coincidence detection, but little is known about …

Hypersensitivity to sounds is one of the prevalent symptoms in individuals with Fragile X
syndrome (FXS). It manifests behaviorally early during development and is often used as a …

Bushy cells in the ventral cochlear nucleus convey firing of auditory nerve fibers to neurons
in the superior olivary complex that compare the timing and intensity of sounds at the two …

Synaptic transmission at the inner hair cell (IHC) afferent synapse, the first synapse in the
auditory pathway, is specialized for rapid and reliable signaling. Here we investigated the …

Since their discovery, naked mole-rats have been speaking to us. Early field studies noted
their extensive vocalizations, and scientists who are fortunate enough to spend time with …