Chemotherapy has an essential role not only in advanced solid tumor therapy intervention
but also in society's health at large. Chemoresistance, however, seriously restricts the …

We present a review of porosity and diffusion in biological tissues from different
perspectives. We first introduce the topic by illustrating experimental evidence related to …

To exploit the benefits of a multifunctional nanomaterial as theranostics, drug carriers, and
adjuvant therapeutics, tissue parameters affecting in-vivo transport, intratumoral diffusion …

In this study, a novel multi-scale and multi-physics image-based computational model is
introduced to assess the delivery of doxorubicin (Dox) loaded temperature-sensitive …

A new mathematical model for the macroscopic behavior of a material composed of a
poroelastic solid embedding a Newtonian fluid network phase (also referred to as …

We describe a novel mathematical model for blood flow, delivery of nanoparticles, and heat
transport in vascularised tumour tissue. The model, which is derived via the asymptotic …

We derive the homogenized governing equations for a double porosity system where the
fluid flow within the individual compartments is governed by the coupling between the Darcy …

We investigate the dependence of the mechanical and hydraulic properties of poroelastic
materials on the interstitial volume fraction (porosity) of the fluid flowing through their pores …

The present work focuses on the integration of analytical and numerical strategies to
investigate the thermal distribution of cancerous breasts. Coupled stationary bioheat transfer …

In this work we address the role of the microstructural properties of a vascularised
poroelastic material, characterised by the coupling between a poroelastic matrix and a …