Microbial metabolites in the marine carbon cycle
One-quarter of photosynthesis-derived carbon on Earth rapidly cycles through a set of short-
lived seawater metabolites that are generated from the activities of marine phytoplankton …
lived seawater metabolites that are generated from the activities of marine phytoplankton …
NMR and metabolomics—A roadmap for the future
Metabolomics investigates global metabolic alterations associated with chemical, biological,
physiological, or pathological processes. These metabolic changes are measured with …
physiological, or pathological processes. These metabolic changes are measured with …
In-cell NMR: Why and how?
NMR spectroscopy has been applied to cells and tissues analysis since its beginnings, as
early as 1950. We have attempted to gather here in a didactic fashion the broad diversity of …
early as 1950. We have attempted to gather here in a didactic fashion the broad diversity of …
NMR: unique strengths that enhance modern metabolomics research
Nuclear magnetic resonance (NMR) spectroscopy is an important analytical technique in
metabolomics. Because it provides atomic-level detail of small molecules, NMR is …
metabolomics. Because it provides atomic-level detail of small molecules, NMR is …
INCA 2.0: A tool for integrated, dynamic modeling of NMR-and MS-based isotopomer measurements and rigorous metabolic flux analysis
Metabolic flux analysis (MFA) combines experimental measurements and computational
modeling to determine biochemical reaction rates in live biological systems. Advancements …
modeling to determine biochemical reaction rates in live biological systems. Advancements …
Metabolic collateral lethal target identification reveals MTHFD2 paralogue dependency in ovarian cancer
Recurrent loss-of-function deletions cause frequent inactivation of tumour suppressor genes
but often also involve the collateral deletion of essential genes in chromosomal proximity …
but often also involve the collateral deletion of essential genes in chromosomal proximity …
[HTML][HTML] Metabolomics and modelling approaches for systems metabolic engineering
JK Khanijou, H Kulyk, C Bergès, LW Khoo, P Ng… - Metabolic Engineering …, 2022 - Elsevier
Metabolic engineering involves the manipulation of microbes to produce desirable
compounds through genetic engineering or synthetic biology approaches. Metabolomics …
compounds through genetic engineering or synthetic biology approaches. Metabolomics …
Connecting metabolome and phenotype: recent advances in functional metabolomics tools for the identification of bioactive natural products
Covering: 1995 to 2023Advances in bioanalytical methods, particularly mass spectrometry,
have provided valuable molecular insights into the mechanisms of life. Non-targeted …
have provided valuable molecular insights into the mechanisms of life. Non-targeted …
In vivo NMR spectroscopy
Understanding biological processes at the molecular level is a pillar of modern science, and
unique insight can be gained by studying living organisms in real time. As a non-destructive …
unique insight can be gained by studying living organisms in real time. As a non-destructive …
Single cell metabolomics: a future tool to unmask cellular heterogeneity and virus-host interaction in context of emerging viral diseases
Viral emergence is an unpredictable but obvious event, particularly in the era of climate
change and globalization. Efficient management of viral outbreaks depends on pre-existing …
change and globalization. Efficient management of viral outbreaks depends on pre-existing …