Mechanisms of estrogen influence on skeletal muscle: mass, regeneration, and mitochondrial function

A Pellegrino, PM Tiidus, R Vandenboom - Sports medicine, 2022 - Springer
Human menopause is widely associated with impaired skeletal muscle quality and
significant metabolic dysfunction. These observations pose significant challenges to the …

Sex differences in cancer cachexia

X Zhong, TA Zimmers - Current Osteoporosis Reports, 2020 - Springer
Abstract Purpose of Review Cachexia, a feature of cancer and other chronic diseases, is
marked by progressive weight loss and skeletal muscle wasting. This review aims to …

Sex specificity of pancreatic cancer cachexia phenotypes, mechanisms, and treatment in mice and humans: role of Activin

X Zhong, A Narasimhan, LM Silverman… - Journal of cachexia …, 2022 - Wiley Online Library
Background Cachexia is frequent, deadly, and untreatable for patients with pancreatic ductal
adenocarcinoma (PDAC). The reproductive hormone and cytokine Activin is a mediator of …

Cancer‐associated malnutrition and CT‐defined sarcopenia and myosteatosis are endemic in overweight and obese patients

L Martin, I Gioulbasanis, P Senesse… - Journal of Parenteral …, 2020 - Wiley Online Library
Background Overweight/obese patients' large fat mass can mask the loss of skeletal muscle,
which is associated with mortality in the oncology setting. We investigated the prevalence of …

Cancer cachexia and skeletal muscle atrophy in clinical studies: what do we really know?

A Dolly, JF Dumas, S Servais - Journal of Cachexia …, 2020 - Wiley Online Library
Research investigators have shown a growing interest in investigating alterations underlying
skeletal muscle wasting in patients with cancer. However, skeletal muscle dysfunctions …

[HTML][HTML] Physical activity as the best supportive care in cancer: the clinician's and the researcher's perspectives

C Torregrosa, F Chorin, EEM Beltran, C Neuzillet… - Cancers, 2022 - mdpi.com
Simple Summary This literature review on adapted physical exercise has been written in
order to raise awareness of medical staff to this central theme in the management of cancer …

Ketone bodies attenuate wasting in models of atrophy

AP Koutnik, AM Poff, NP Ward… - Journal of cachexia …, 2020 - Wiley Online Library
Abstract Background Cancer Anorexia Cachexia Syndrome (CACS) is a distinct atrophy
disease negatively influencing multiple aspects of clinical care and patient quality of life …

Cancer cachexia in a mouse model of oxidative stress

JL Brown, MM Lawrence, B Ahn, P Kneis… - Journal of cachexia …, 2020 - Wiley Online Library
Background Cancer is associated with muscle atrophy (cancer cachexia) that is linked to up
to 40% of cancer‐related deaths. Oxidative stress is a critical player in the induction and …

Association between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio and sarcopenia in individuals with cancer: a cross-sectional …

R He, Y Ye, Q Zhu, C **e - Lipids in Health and Disease, 2024 - Springer
Background Cancer and sarcopenia are both closely related to lipid metabolism, but the
relationship between lipid metabolism and patients with cancer and sarcopenia has not …

Skeletal muscle wasting: The estrogen side of sexual dimorphism

SL McMillin, EC Minchew, DA Lowe… - American Journal of …, 2022 - journals.physiology.org
The importance of defining sex differences across various biological and physiological
mechanisms is more pervasive now than it has been over the past 15–20 years. As the …