Macrophages, found in circulating blood as well as integrated into several tissues and
organs throughout the body, represent an important first line of defense against disease and …

Mesenchymal stem cells (MSC) can be isolated from different adult tissues including bone
marrow, adipose tissue, cord blood and placenta. MSCs modulate the immune function of …

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Kaposi's sarcoma had been recognized as unique human cancer for a century before it
manifested as an AIDS-defining illness with a suspected infectious etiology. The discovery of …

Kaposi sarcoma–associated herpesvirus (KSHV), or human herpervirus 8 (HHV-8), is a γ-
herpesvirus that infects human lymphocytes and is associated with primary effusion …

Soon after the discovery of Kaposi sarcoma (KS)-associated herpesvirus (KSHV), it was
appreciated that this virus was associated with most cases of multicentric Castleman …

The NLR (nucleotide binding and oligomerization, leucine-rich repeat) family of proteins
senses microbial infections and activates the inflammasome, a multiprotein complex that …

The capacity of macrophages to support productive HIV-1 infection is known to be
modulated by cytokines and other extracellular stimuli. In this study, we demonstrate that …

Kaposi sarcoma herpesvirus (KSHV), taxonomical name human gammaherpesvirus 8, is a
phylogenetically old human virus that co-evolved with human populations, but is now only …

Abstract Treatment with HIV-1 protease inhibitors (PI) is associated with a reduced incidence
or regression of Kaposi sarcoma (KS). Here we show that systemic administration of the PIs …