The electromechanical function of the heart involves complex, coordinated activity over time
and space. Life-threatening cardiac arrhythmias arise from asynchrony in these space–time …

The heart is vital for biological function in almost all chordates, including humans. It beats
continually throughout our life, supplying the body with oxygen and nutrients while removing …

Heart rate is under the precise control of the autonomic nervous system. However, the wiring
of peripheral neural circuits that regulate heart rate is poorly understood. Here, we develop a …

The cardiac autonomic nervous system (CANS) plays a key role for the regulation of cardiac
activity with its dysregulation being involved in various heart diseases, such as cardiac …

The preoptic area (POA) is a key brain region for regulation of body temperature (Tb),
dictating thermogenic, cardiovascular, and behavioral responses that control Tb. Previously …

Optogenetic techniques permit studies of excitable tissue through genetically expressed
light-gated microbial channels or pumps permitting transmembrane ion movement. Light …

Autonomic imbalance is an important characteristic of patients after myocardial infarction
(MI) and adversely contributes to post‐MI cardiac remodeling and ventricular arrhythmias …

The heterogeneity of functional cardiomyocytes arises during heart development, which is
essential to the complex and highly coordinated cardiac physiological function. Yet the …

Remodeling of injured sympathetic nerves on the heart after myocardial infarction (MI)
contributes to adverse outcomes such as sudden arrhythmic death, yet the underlying …

Sympathetic neurons densely innervate the myocardium with non‐random topology and
establish structured contacts (ie neuro‐cardiac junctions, NCJ) with cardiomyocytes …