The impact of the human thalamus on brain-wide information processing

JM Shine, LD Lewis, DD Garrett… - Nature Reviews …, 2023 - nature.com
The thalamus is a small, bilateral structure in the diencephalon that integrates signals from
many areas of the CNS. This critical anatomical position allows the thalamus to influence …

Mechanisms underlying dorsolateral prefrontal cortex contributions to cognitive dysfunction in schizophrenia

J Smucny, SJ Dienel, DA Lewis… - …, 2022 - nature.com
Kraepelin, in his early descriptions of schizophrenia (SZ), characterized the illness as having
“an orchestra without a conductor.” Kraepelin further speculated that this “conductor” was …

Heterogeneous aging across multiple organ systems and prediction of chronic disease and mortality

YE Tian, V Cropley, AB Maier, NT Lautenschlager… - Nature medicine, 2023 - nature.com
Biological aging of human organ systems reflects the interplay of age, chronic disease,
lifestyle and genetic risk. Using longitudinal brain imaging and physiological phenotypes …

SARS-CoV-2 is associated with changes in brain structure in UK Biobank

G Douaud, S Lee, F Alfaro-Almagro, C Arthofer… - Nature, 2022 - nature.com
There is strong evidence of brain-related abnormalities in COVID-19,,,,,,,,,,,–. However, it
remains unknown whether the impact of SARS-CoV-2 infection can be detected in milder …

SynthSeg: Segmentation of brain MRI scans of any contrast and resolution without retraining

B Billot, DN Greve, O Puonti, A Thielscher… - Medical image …, 2023 - Elsevier
Despite advances in data augmentation and transfer learning, convolutional neural
networks (CNNs) difficultly generalise to unseen domains. When segmenting brain scans …

Robust machine learning segmentation for large-scale analysis of heterogeneous clinical brain MRI datasets

B Billot, C Magdamo, Y Cheng, SE Arnold… - Proceedings of the …, 2023 - pnas.org
Every year, millions of brain MRI scans are acquired in hospitals, which is a figure
considerably larger than the size of any research dataset. Therefore, the ability to analyze …

[HTML][HTML] Automated anatomical labelling atlas 3

ET Rolls, CC Huang, CP Lin, J Feng, M Joliot - Neuroimage, 2020 - Elsevier
Following a first version AAL of the automated anatomical labeling atlas (Tzourio-Mazoyer et
al., 2002), a second version (AAL2)(Rolls et al., 2015) was developed that provided an …

Multimodal MRI reveals brainstem connections that sustain wakefulness in human consciousness

BL Edlow, M Olchanyi, HJ Freeman, J Li… - Science Translational …, 2024 - science.org
Consciousness is composed of arousal (ie, wakefulness) and awareness. Substantial
progress has been made in map** the cortical networks that underlie awareness in the …

Brain imaging before and after COVID-19 in UK Biobank

G Douaud, S Lee, F Alfaro-Almagro, C Arthofer… - MedRxiv, 2021 - medrxiv.org
There is strong evidence for brain-related pathologies in COVID-19, some of which could be
a consequence of viral neurotropism, or of neuroinflammation following viral infection. Most …

Thalamus Optimized Multi Atlas Segmentation (THOMAS): fast, fully automated segmentation of thalamic nuclei from structural MRI

JH Su, FT Thomas, WS Kasoff, T Tourdias, EY Choi… - Neuroimage, 2019 - Elsevier
The thalamus and its nuclei are largely indistinguishable on standard T1 or T2 weighted
MRI. While diffusion tensor imaging based methods have been proposed to segment the …