Hybracter: enabling scalable, automated, complete and accurate bacterial genome assemblies

G Bouras, G Houtak, RR Wick… - Microbial …, 2024 - microbiologyresearch.org
Improvements in the accuracy and availability of long-read sequencing mean that complete
bacterial genomes are now routinely reconstructed using hybrid (ie short-and long-reads) …

Plassembler: an automated bacterial plasmid assembly tool

G Bouras, AE Sheppard, V Mallawaarachchi… - …, 2023 - academic.oup.com
With recent advances in sequencing technologies, it is now possible to obtain near-perfect
complete bacterial chromosome assemblies cheaply and efficiently by combining a long …

Phables: from fragmented assemblies to high-quality bacteriophage genomes

V Mallawaarachchi, MJ Roach, P Decewicz… - …, 2023 - academic.oup.com
Motivation Microbial communities have a profound impact on both human health and
various environments. Viruses infecting bacteria, known as bacteriophages or phages, play …

Solving genomic puzzles: computational methods for metagenomic binning

V Mallawaarachchi, A Wickramarachchi… - Briefings in …, 2024 - academic.oup.com
Metagenomics involves the study of genetic material obtained directly from communities of
microorganisms living in natural environments. The field of metagenomics has provided …

A FAIR and modular image‐based workflow for knowledge discovery in the emerging field of imageomics

MA Balk, J Bradley, M Maruf, B Altintaş… - Methods in ecology …, 2024 - Wiley Online Library
Image‐based machine learning tools are an ascendant 'big data'research avenue. Citizen
science platforms, like iNaturalist, and museum‐led initiatives provide researchers with an …

Hecatomb: an integrated software platform for viral metagenomics

MJ Roach, SJ Beecroft, KA Mihindukulasuriya… - …, 2024 - academic.oup.com
Background Modern sequencing technologies offer extraordinary opportunities for virus
discovery and virome analysis. Annotation of viral sequences from metagenomic data …

Host interactions of novel Crassvirales species belonging to multiple families infecting bacterial host, Bacteroides cellulosilyticus WH2

B Papudeshi, AA Vega, C Souza… - Microbial …, 2023 - microbiologyresearch.org
Bacteroides, the prominent bacteria in the human gut, play a crucial role in degrading
complex polysaccharides. Their abundance is influenced by phages belonging to the …

Staphylococcus aureus Biofilm-Secreted Factors Cause Mucosal Damage, Mast Cell Infiltration, and Goblet Cell Hyperplasia in a Rat Rhinosinusitis Model

G Houtak, R Nepal, G Bouras, G Shaghayegh… - International Journal of …, 2024 - mdpi.com
Chronic rhinosinusitis (CRS) is an inflammatory condition of the sinonasal mucosa. Despite
being a common health issue, the exact cause of CRS is yet to be understood. However …

[PDF][PDF] Koverage: read-coverage analysis for massive (meta) genomics datasets

MJ Roach, BJ Hart, SJ Beecroft… - Journal of Open …, 2024 - joss.theoj.org
Genomes of organisms are constructed by assembling sequence reads from whole genome
sequencing. It is useful to determine sequence read-coverage of genome assemblies, for …

CLAW: An automated Snakemake workflow for the assembly of chloroplast genomes from long-read data

AL Phillips, S Ferguson, RA Burton… - PLOS Computational …, 2024 - journals.plos.org
Chloroplasts are photosynthetic organelles in algal and plant cells that contain their own
genome. Chloroplast genomes are commonly used in evolutionary studies and taxonomic …