Small RNAs, large networks: posttranscriptional regulons in gram-negative bacteria

K Papenfort, S Melamed - Annual review of microbiology, 2023 - annualreviews.org
Small regulatory RNA (sRNAs) are key mediators of posttranscriptional gene control in
bacteria. Assisted by RNA-binding proteins, a single sRNA often modulates the expression …

Trans-Acting Small RNAs and Their Effects on Gene Expression in Escherichia coli and Salmonella enterica

J Hör, G Matera, J Vogel, S Gottesman, G Storz - EcoSal Plus, 2020 - journals.asm.org
The last few decades have led to an explosion in our understanding of the major roles that
small regulatory RNAs (sRNAs) play in regulatory circuits and the responses to stress in …

Biomimetic macrophage membrane-camouflaged nanoparticles induce ferroptosis by promoting mitochondrial damage in glioblastoma

Z Cao, X Liu, W Zhang, K Zhang, L Pan, M Zhu, H Qin… - ACS …, 2023 - ACS Publications
The increasing understanding of ferroptosis has indicated its role and therapeutic potential
in cancer; however, this knowledge has yet to be translated into effective therapies …

Small RNAs in bacteria and archaea: who they are, what they do, and how they do it

EGH Wagner, P Romby - Advances in genetics, 2015 - Elsevier
Small RNAs are ubiquitously present regulators in all kingdoms of life. Most bacterial and
archaeal small RNAs (sRNAs) act by antisense mechanisms on multiple target mRNAs …

IntaRNA 2.0: enhanced and customizable prediction of RNA–RNA interactions

M Mann, PR Wright, R Backofen - Nucleic acids research, 2017 - academic.oup.com
The IntaRNA algorithm enables fast and accurate prediction of RNA–RNA hybrids by
incorporating seed constraints and interaction site accessibility. Here, we introduce …

RNA-binding proteins in bacteria

E Holmqvist, J Vogel - Nature Reviews Microbiology, 2018 - nature.com
RNA-binding proteins (RBPs) are central to most if not all cellular processes, dictating the
fate of virtually all RNA molecules in the cell. Starting with pioneering work on ribosomal …

Dual RNA-seq of pathogen and host

AJ Westermann, SA Gorski, J Vogel - Nature Reviews Microbiology, 2012 - nature.com
A comprehensive understanding of host–pathogen interactions requires a knowledge of the
associated gene expression changes in both the pathogen and the host. Traditional, probe …

An infection-relevant transcriptomic compendium for Salmonella enterica Serovar Typhimurium

C Kröger, A Colgan, S Srikumar, K Händler… - Cell host & …, 2013 - cell.com
Bacterial transcriptional networks consist of hundreds of transcription factors and thousands
of promoters. However, the true complexity of transcription in a bacterial pathogen and the …

Global RNA recognition patterns of post‐transcriptional regulators Hfq and CsrA revealed by UV crosslinking in vivo

E Holmqvist, PR Wright, L Li, T Bischler… - The EMBO …, 2016 - embopress.org
The molecular roles of many RNA‐binding proteins in bacterial post‐transcriptional gene
regulation are not well understood. Approaches combining in vivo UV crosslinking with RNA …

In vivo cleavage map illuminates the central role of RNase E in coding and non-coding RNA pathways

Y Chao, L Li, D Girodat, KU Förstner, N Said… - Molecular cell, 2017 - cell.com
Understanding RNA processing and turnover requires knowledge of cleavages by major
endoribonucleases within a living cell. We have employed TIER-seq (transiently inactivating …