Three‑dimensional cell culture: A powerful tool in tumor research and drug discovery
D Lv, Z Hu, L Lu, H Lu, X Xu - Oncology letters, 2017 - spandidos-publications.com
In previous years, three‑dimensional (3D) cell culture technology has become a focus of
research in tumor cell biology, using a variety of methods and materials to mimic the in vivo …
research in tumor cell biology, using a variety of methods and materials to mimic the in vivo …
Biomaterial-based platforms for tumour tissue engineering
Tissue engineering has produced innovative tools for cancer research. 3D cancer models
based on molecularly designed biomaterials aim to harness the dimensionality and …
based on molecularly designed biomaterials aim to harness the dimensionality and …
Functionalization, preparation and use of cell-laden gelatin methacryloyl–based hydrogels as modular tissue culture platforms
Progress in advancing a system-level understanding of the complexity of human tissue
development and regeneration is hampered by a lack of biological model systems that …
development and regeneration is hampered by a lack of biological model systems that …
Three-dimensional printing of Hela cells for cervical tumor model in vitro
Advances in three-dimensional (3D) printing have enabled the direct assembly of cells and
extracellular matrix materials to form in vitro cellular models for 3D biology, the study of …
extracellular matrix materials to form in vitro cellular models for 3D biology, the study of …
Remodelling of the tumour microenvironment by the kallikrein-related peptidases
Kallikrein-related peptidases (KLKs) are critical regulators of the tumour microenvironment.
KLKs are proteolytic enzymes regulating multiple functions of bioactive molecules including …
KLKs are proteolytic enzymes regulating multiple functions of bioactive molecules including …
Designer self‐assembling peptide hydrogels to engineer 3D cell microenvironments for cell constructs formation and precise oncology remodeling in ovarian cancer
Z Yang, H Xu, X Zhao - Advanced Science, 2020 - Wiley Online Library
Designer self‐assembling peptides form the entangled nanofiber networks in hydrogels by
ionic‐complementary self‐assembly. This type of hydrogel has realistic biological and …
ionic‐complementary self‐assembly. This type of hydrogel has realistic biological and …
3D bioprinting: improving in vitro models of metastasis with heterogeneous tumor microenvironments
JL Albritton, JS Miller - Disease models & mechanisms, 2017 - journals.biologists.com
Even with many advances in treatment over the past decades, cancer still remains a leading
cause of death worldwide. Despite the recognized relationship between metastasis and …
cause of death worldwide. Despite the recognized relationship between metastasis and …
Gelatine methacrylamide-based hydrogels: An alternative three-dimensional cancer cell culture system
Modern cancer research requires physiological, three-dimensional (3-D) cell culture
platforms, wherein the physical and chemical characteristics of the extracellular matrix …
platforms, wherein the physical and chemical characteristics of the extracellular matrix …
The role of tumor microenvironment in chemoresistance: 3D extracellular matrices as accomplices
DA Senthebane, T Jonker, A Rowe… - International journal of …, 2018 - mdpi.com
Background: The functional interplay between tumor cells and their adjacent stroma has
been suggested to play crucial roles in the initiation and progression of tumors and the …
been suggested to play crucial roles in the initiation and progression of tumors and the …
Microfluidic 3D models of cancer
Despite advances in medicine and biomedical sciences, cancer still remains a major health
issue. Complex interactions between tumors and their microenvironment contribute to tumor …
issue. Complex interactions between tumors and their microenvironment contribute to tumor …