Aging is characterized by systemic chronic inflammation, which is accompanied by cellular
senescence, immunosenescence, organ dysfunction, and age-related diseases. Given the …

Acute inflammation is a physiological response to injury or infection, with a cascade of steps
that ultimately lead to the recruitment of immune cells to clear invading pathogens and heal …

Aging is the greatest risk factor for nearly all major chronic diseases, including
cardiovascular diseases, cancer, Alzheimer's and other neurodegenerative diseases of …

Physiological ageing is accompanied by decline in immune system function and immune
alteration during ageing increases susceptibility to infections. We retrospectively analysed …

The concept of immunosenescence reflects age-related changes in immune responses,
both cellular and serological, affecting the process of generating specific responses to …

Publisher Summary Studies of cytotoxicity by human lymphocytes revealed not only that
both allogeneic and syngeneic tumor cells were lysed in a non-MHC-restricted fashion, but …

The past decade has seen an explosion in research focusing on innate immunity. Through a
wide range of mechanisms including phagocytosis, intracellular killing and activation of …

Human aging is characterized by both physical and physiological frailty. A key feature of
frailty, sarcopenia is the age-associated decline in skeletal muscle mass, strength, and …

Forming the first line of defence against virally infected and malignant cells, natural killer
(NK) cells are critical effector cells of the innate immune system. With age, significant …

The relationship between cardiorespiratory exercise, immune function, and upper
respiratory tract infection (URTI) was studied in elderly women utilizing a randomized …