Current concepts in the pathogenesis of periodontitis: from symbiosis to dysbiosis

AA Abdulkareem, FB Al-Taweel… - Journal of Oral …, 2023 - Taylor & Francis
The primary etiological agent for the initiation and progression of periodontal disease is the
dental plaque biofilm which is an organized aggregation of microorganisms residing within a …

The oral microbiome: Role of key organisms and complex networks in oral health and disease

L Sedghi, V DiMassa, A Harrington… - Periodontology …, 2021 - Wiley Online Library
States of oral health and disease reflect the compositional and functional capacities of, as
well as the interspecies interactions within, the oral microbiota. The oral cavity exists as a …

Periodontal disease: the good, the bad, and the unknown

LM Sedghi, M Bacino, YL Kapila - Frontiers in cellular and infection …, 2021 - frontiersin.org
Periodontal disease is classically characterized by progressive destruction of the soft and
hard tissues of the periodontal complex, mediated by an interplay between dysbiotic …

Promising dawn in tumor microenvironment therapy: engineering oral bacteria

Z Wang, W Sun, R Hua, Y Wang, Y Li… - International Journal of …, 2024 - nature.com
Despite decades of research, cancer continues to be a major global health concern. The
human mouth appears to be a multiplicity of local environments communicating with other …

Periodontal microbiology and microbial etiology of periodontal diseases: Historical concepts and contemporary perspectives

GN Belibasakis, D Belstrøm, S Eick… - Periodontology …, 2023 - Wiley Online Library
This narrative review summarizes the collective knowledge on periodontal microbiology,
through a historical timeline that highlights the European contribution in the global field. The …

Impact of oral microbiome in periodontal health and periodontitis: a critical review on prevention and treatment

M Di Stefano, A Polizzi, S Santonocito… - International journal of …, 2022 - mdpi.com
The skin, oral cavity, digestive and reproductive tracts of the human body harbor symbiotic
and commensal microorganisms living harmoniously with the host. The oral cavity houses …

Microbial signatures of health, gingivitis, and periodontitis

L Abusleme, A Hoare, BY Hong, PI Diaz - Periodontology 2000, 2021 - Wiley Online Library
The subgingival crevice harbors diverse microbial communities. Shifts in the composition of
these communities occur with the development of gingivitis and periodontitis, which are …

In silico validation of the non‐antibiotic drugs acetaminophen and ibuprofen as antibacterial agents against red complex pathogens

J Vijayashree Priyadharsini - Journal of periodontology, 2019 - Wiley Online Library
Background Acetaminophen (APAP) and ibuprofen (IB) are drugs commonly used to
alleviate pain due to their anti‐inflammatory, anti‐pyretic, and analgesic effect. The aim of …

[HTML][HTML] The oralome and its dysbiosis: New insights into oral microbiome-host interactions

A Radaic, YL Kapila - Computational and structural biotechnology journal, 2021 - Elsevier
The oralome is the summary of the dynamic interactions orchestrated between the
ecological community of oral microorganisms (comprised of up to approximately 1000 …

The oral microbiota: dynamic communities and host interactions

RJ Lamont, H Koo, G Hajishengallis - Nature reviews microbiology, 2018 - nature.com
The dynamic and polymicrobial oral microbiome is a direct precursor of diseases such as
dental caries and periodontitis, two of the most prevalent microbially induced disorders …