Neuroinflammation in Alzheimer's disease: current progress in molecular signaling and therapeutics

S Thakur, R Dhapola, P Sarma, B Medhi, DHK Reddy - Inflammation, 2023 - Springer
Alzheimer's disease, a neurodegenerative disease with amyloid beta accumulation as a
major hallmark, has become a dire global health concern as there is a lack of clear …

Mitochondrial dysfunction in neurodegenerative diseases and drug targets via apoptotic signaling

Y Wu, M Chen, J Jiang - Mitochondrion, 2019 - Elsevier
Mitochondrial dysfunction is becoming one of the most emerging pathological process in the
etiology of neurological disorders. Other common etiologies of the neurological disorders …

Neuroprotective natural products for Alzheimer's disease

X Chen, J Drew, W Berney, W Lei - Cells, 2021 - mdpi.com
Alzheimer's disease (AD) is the number one neurovegetative disease, but its treatment
options are relatively few and ineffective. In efforts to discover new strategies for AD therapy …

Epigallocatechin-3-Gallate (EGCG): New therapeutic perspectives for neuroprotection, aging, and neuroinflammation for the modern age

A Payne, S Nahashon, E Taka, GM Adinew… - Biomolecules, 2022 - mdpi.com
Alzheimer's and Parkinson's diseases are the two most common forms of neurodegenerative
diseases. The exact etiology of these disorders is not well known; however, environmental …

Impact of natural compounds on neurodegenerative disorders: from preclinical to pharmacotherapeutics

M Sharifi-Rad, C Lankatillake, DA Dias… - Journal of Clinical …, 2020 - mdpi.com
Among the major neurodegenerative disorders (NDDs), Alzheimer's disease (AD) and
Parkinson's disease (PD), are a huge socioeconomic burden. Over many centuries, people …

[HTML][HTML] Anti-inflammatory activity of phytochemicals from medicinal plants and their nanoparticles: A review

YH Gonfa, FB Tessema, A Bachheti, N Rai… - Current Research in …, 2023 - Elsevier
Plant-based phytochemicals are known for their potential sources of anti-inflammatory
agents. Various studies reported the potential disease-healing efficiency of medicinal plants' …

Neuroprotective effect of quercetin against the detrimental effects of LPS in the adult mouse brain

A Khan, T Ali, SU Rehman, MS Khan, SI Alam… - Frontiers in …, 2018 - frontiersin.org
Chronic neuroinflammation is responsible for multiple neurodegenerative diseases, such as
Alzheimer's disease, Parkinson's disease, and Huntington's disease. Lipopolysaccharide …

A comprehensive review: Biological activity, modification and synthetic methodologies of prenylated flavonoids

S Shi, J Li, X Zhao, Q Liu, SJ Song - Phytochemistry, 2021 - Elsevier
Prenylated flavonoids, a unique class of flavonoids which combine a flavonoid skeleton and
a lipophilic prenyl side-chain, possess great potential biological activities including …

[HTML][HTML] Therapeutic applications of mushrooms and their biomolecules along with a glimpse of in silico approach in neurodegenerative diseases

SN Rai, D Mishra, P Singh, E Vamanu… - Biomedicine & …, 2021 - Elsevier
Neurodegenerative diseases (NDs) represent a common neurological pathology that
determines a progressive deterioration of the brain or the nervous system. For treating NDs …

Acetylcholinesterase inhibitory potential of various sesquiterpene analogues for Alzheimer's disease therapy

A Arya, R Chahal, R Rao, MH Rahman, D Kaushik… - Biomolecules, 2021 - mdpi.com
Alzheimer's disease (AD) is a gradually growing irreversible illness of the brain that almost
affects every fifth person (aged> 80 years) in the world. World Health Organization (WHO) …